p-Coumaric acid

About p-Coumaric acid

p-Coumaric acid is a metabolite or degradation product of Esmolol carrying the CAS registry number 7400-08-0. Formula C9H8O3, molecular weight 164.16 g/mol. Systematically, it is named (E)-3-(4-hydroxyphenyl)prop-2-enoic acid. It is also known as trans-p-Coumaric acid or Hydroxycinnamic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Esmolol, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer p-Coumaric acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Esmolol

View every impurity, metabolite and intermediate we list for Esmolol.

Esmolol impurities

Specifications & identifiers

Chemical identifiers
Product name	p-Coumaric acid
Catalogue No.	VQ-045220
CAS Number	7400-08-0
IUPAC name	(E)-3-(4-hydroxyphenyl)prop-2-enoic acid
Molecular formula	C₉H₈O₃
Molecular weight	164.16 g/mol
Exact mass	164.0473
Grade	Reference Standard
HSN code	38229090
InChIKey	NGSWKAQJJWESNS-ZZXKWVIFSA-N
SMILES	C1=CC(=CC=C1/C=C/C(=O)O)O
PubChem CID	637542

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	trans-p-Coumaric acid, Hydroxycinnamic acid, Para-Coumaric acid, Naringeninic acid, (E)-p-Coumaric acid, trans-4-coumaric acid, trans-p-Hydroxycinnamic acid, trans-p-Coumarinic acid, 4'-hydroxycinnamic acid, (E)-p-Hydroxycinnamic acid, 2-propenoic acid, 3-(4-hydroxyphenyl)-, (2E)-, p-Hydroxyphenylacrylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of p-Coumaric acid?

The CAS Registry Number of p-Coumaric acid is 7400-08-0. It is also known as trans-p-Coumaric acid, Hydroxycinnamic acid, Para-Coumaric acid.

What is the molecular formula and molecular weight of p-Coumaric acid?

p-Coumaric acid has the molecular formula C9H8O3 and a molecular weight of 164.16 g/mol. Its IUPAC name is (E)-3-(4-hydroxyphenyl)prop-2-enoic acid.

What is p-Coumaric acid used for?

p-Coumaric acid is supplied as a characterised reference material related to Esmolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of p-Coumaric acid can I order?

We supply p-Coumaric acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with p-Coumaric acid?

Yes. Every lot of p-Coumaric acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can p-Coumaric acid be shipped internationally?

Yes. p-Coumaric acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.