Ketorolac Tromethamine

About Ketorolac Tromethamine

Ketorolac Tromethamine is a high-purity reference standard of Ketorolac carrying the CAS registry number 74103-07-4. With the molecular formula C19H24N2O6, it has a molar mass of 376.4 g/mol. Its systematic (IUPAC) name is 2-amino-2-(hydroxymethyl)propane-1,3-diol, 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. Alternative names: Ketorolac tris salt and Ketorolac Tromethamine Salt.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Ketorolac, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ketorolac

View every impurity, metabolite and intermediate we list for Ketorolac.

Ketorolac impurities

Specifications & identifiers

Chemical identifiers
Product name	Ketorolac Tromethamine
Catalogue No.	VQ-007516
CAS Number	74103-07-4
Other CAS	74103-06-3, 110618-38-7, 167105-81-9, 218934-99-7
IUPAC name	2-amino-2-(hydroxymethyl)propane-1,3-diol;5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Molecular formula	C₁₉H₂₄N₂O₆
Molecular weight	376.4 g/mol
Exact mass	376.1634
Grade	Reference Standard
HSN code	38229090
InChIKey	BWHLPLXXIDYSNW-UHFFFAOYSA-N
SMILES	C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O
PubChem CID	84003

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 7
TPSA	146 Å²
Synonyms	Ketorolac tris salt, (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid Tris Salt, Ketorolac Tromethamine Salt, Ketorolac Trometamol, rac Ketorolac Tromethamine Salt, Trometamol Ketorolac, Dolac, Ketanov, Ketorol, Toradol, Toratex, Lixidol

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketorolac Tromethamine?

The CAS Registry Number of Ketorolac Tromethamine is 74103-07-4. It is also known as Ketorolac tris salt, (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid Tris Salt, Ketorolac Tromethamine Salt.

What is the molecular formula and molecular weight of Ketorolac Tromethamine?

Ketorolac Tromethamine has the molecular formula C19H24N2O6 and a molecular weight of 376.4 g/mol.

What is Ketorolac Tromethamine used for?

Ketorolac Tromethamine is supplied as a characterised reference material related to Ketorolac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketorolac Tromethamine can I order?

We supply Ketorolac Tromethamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketorolac Tromethamine?

Yes. Every lot of Ketorolac Tromethamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketorolac Tromethamine be shipped internationally?

Yes. Ketorolac Tromethamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.