Ketorolac EP Impurity A/(Ketorolac USP RC B) 154476-25-2

Name: Ketorolac EP Impurity A/(Ketorolac USP RC B)
Brand: Vaqora Chemicals
SKU: VQ-006438

About Ketorolac EP Impurity A/(Ketorolac USP RC B)

Listed under CAS 154476-25-2, Ketorolac EP Impurity A/(Ketorolac USP RC B) is a pharmacopeial impurity of Ketorolac available from Vaqora Chemicals. With the molecular formula C14H13NO2, it has a molar mass of 227.26 g/mol. The IUPAC name is (7-hydroxy-6,7-dihydro-5H-pyrrolizin-3-yl)-phenylmethanone. Alternative names: Descarboxy 1-Hydroxy Ketorolac and Ketorolac Hydroxy Impurity.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Ketorolac impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Ketorolac

View every impurity, metabolite and intermediate we list for Ketorolac.

Ketorolac impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Ketorolac EP Impurity A/(Ketorolac USP RC B)
Catalogue No.	VQ-006438
CAS Number	154476-25-2
IUPAC name	(7-hydroxy-6,7-dihydro-5H-pyrrolizin-3-yl)-phenylmethanone
Molecular formula	C₁₄H₁₃NO₂
Molecular weight	227.26 g/mol
Exact mass	227.0946
Grade	Reference Standard
HSN code	38229090
InChIKey	PPQHNULBCSHICE-UHFFFAOYSA-N
SMILES	C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1O
PubChem CID	57357558

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 2
TPSA	42.2 Å²
Synonyms	Descarboxy 1-Hydroxy Ketorolac, (2,3-Dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenylmethanone, (1RS)-5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-ol, Ketorolac Hydroxy Impurity, Ketorolac 1-Hydroxy Analogue, Ketorolac Related Compound B (USP), Ketorolac Impurity A, Methanone, (2,3-dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenyl-, 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-ol, (1RS)-, Ketorolac tromethamine impurity, ketorolac 1-hydroxy analog-(USP), Ketorolac trometamol specified impurity A, 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-ol, (+-)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ketorolac EP Impurity A/(Ketorolac USP RC B)?

The CAS Registry Number of Ketorolac EP Impurity A/(Ketorolac USP RC B) is 154476-25-2. It is also known as Descarboxy 1-Hydroxy Ketorolac, (2,3-Dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenylmethanone, (1RS)-5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-ol.

What is the molecular formula and molecular weight of Ketorolac EP Impurity A/(Ketorolac USP RC B)?

Ketorolac EP Impurity A/(Ketorolac USP RC B) has the molecular formula C14H13NO2 and a molecular weight of 227.26 g/mol. Its IUPAC name is (7-hydroxy-6,7-dihydro-5H-pyrrolizin-3-yl)-phenylmethanone.

What is Ketorolac EP Impurity A/(Ketorolac USP RC B) used for?

Ketorolac EP Impurity A/(Ketorolac USP RC B) is supplied as a characterised reference material related to Ketorolac. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ketorolac EP Impurity A/(Ketorolac USP RC B) can I order?

We supply Ketorolac EP Impurity A/(Ketorolac USP RC B) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ketorolac EP Impurity A/(Ketorolac USP RC B)?

Yes. Every lot of Ketorolac EP Impurity A/(Ketorolac USP RC B) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ketorolac EP Impurity A/(Ketorolac USP RC B) be shipped internationally?

Yes. Ketorolac EP Impurity A/(Ketorolac USP RC B) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.