2-Butynol

Name: 2-Butynol
Brand: Vaqora Chemicals
SKU: VQ-012941

About 2-Butynol

Listed under CAS 764-01-2, 2-Butynol is a process intermediate or related compound of Linagliptin available from Vaqora Chemicals at a purity of 90.6%. Formula C4H6O, molecular weight 70.09 g/mol. Systematically, it is named but-2-yn-1-ol. Common synonyms include 1-Hydroxybut-2-yne and 2-Butynyl alcohol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Linagliptin, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Butynol is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Linagliptin

View every impurity, metabolite and intermediate we list for Linagliptin.

Linagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Butynol
Catalogue No.	VQ-012941
CAS Number	764-01-2
IUPAC name	but-2-yn-1-ol
Molecular formula	C₄H₆O
Molecular weight	70.09 g/mol
Exact mass	70.0419
Grade	Reference Standard
Purity / assay	90.6%
InChIKey	NEEDEQSZOUAJMU-UHFFFAOYSA-N
SMILES	CC#CCO
PubChem CID	12991

Physical properties
Physical form	Solid
LogP (XLogP3)	0.2
H-bond donors / acceptors	1 / 1
TPSA	20.2 Å²
Synonyms	1-Hydroxybut-2-yne, 2-Butynyl alcohol, 2-Butyn-1-ol, 3-Methylprop-2-yn-1-ol, 2-Butyne-1-ol, Hydroxymethylmethylacetylene, 2-Butyn-1-ol, 98%, 2-Butynol, 2-butyn-l-ol, 2-butyn1-ol, 2-butin-1-ol, CS-B1382

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Warning

Hazard statements

H226Flammable liquid and vapor
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P233, P240, P241, P242, P243, P261, P264, P264 + P265, P271, P280, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403 + P233, P403 + P235, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Butynol?

The CAS Registry Number of 2-Butynol is 764-01-2. It is also known as 1-Hydroxybut-2-yne, 2-Butynyl alcohol, 2-Butyn-1-ol.

What is the molecular formula and molecular weight of 2-Butynol?

2-Butynol has the molecular formula C4H6O and a molecular weight of 70.09 g/mol. Its IUPAC name is but-2-yn-1-ol.

What is 2-Butynol used for?

2-Butynol is supplied as a characterised reference material related to Linagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Butynol can I order?

We supply 2-Butynol in Reference Standard (90.6%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Butynol?

Yes. Every lot of 2-Butynol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Butynol be shipped internationally?

Yes. 2-Butynol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.