Salicylic Acid-d4

About Salicylic Acid-d4

Salicylic Acid-d4 is a stable isotope labelled analogue related to Salicylic acid carrying the CAS registry number 78646-17-0. Its molecular formula is C7H6O3 and its molecular weight is 142.14 g/mol. Systematically, it is named 2,3,4,5-tetradeuterio-6-hydroxybenzoic acid. Common synonyms include 2-Hydroxy(~2~H_4_)benzoic acid and 2-Carboxyphenol-d4.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Salicylic acid and related analytes in bioanalytical, pharmacokinetic and impurity studies. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Salicylic acid

View every impurity, metabolite and intermediate we list for Salicylic acid.

Salicylic acid impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Salicylic Acid-d4
Catalogue No.	VQ-033748
CAS Number	78646-17-0
IUPAC name	2,3,4,5-tetradeuterio-6-hydroxybenzoic acid
Molecular formula	C₇H₆O₃
Molecular weight	142.14 g/mol
Exact mass	142.0568
Grade	Reference Standard
HSN code	38229090
InChIKey	YGSDEFSMJLZEOE-RHQRLBAQSA-N
SMILES	[2H]C1=C(C(=C(C(=C1[2H])C(=O)O)O)[2H])[2H]
PubChem CID	46782907

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	2-Hydroxy(~2~H_4_)benzoic acid, 2-Carboxyphenol-d4, 2-Hydroxybenzoic Acid-d4, 2,3,4,5-tetradeuterio-6-hydroxy-benzoic acid, d4-salicylic acid, Salicylic Acid-3,4,5,6-d4, TMIH-0513

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H318Causes serious eye damage

Precautionary statements: P203, P264, P264 + P265, P270, P280, P301 + P317, P305 + P354 + P338, P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Salicylic Acid-d4?

The CAS Registry Number of Salicylic Acid-d4 is 78646-17-0. It is also known as 2-Hydroxy(~2~H_4_)benzoic acid, 2-Carboxyphenol-d4, 2-Hydroxybenzoic Acid-d4.

What is the molecular formula and molecular weight of Salicylic Acid-d4?

Salicylic Acid-d4 has the molecular formula C7H6O3 and a molecular weight of 142.14 g/mol. Its IUPAC name is 2,3,4,5-tetradeuterio-6-hydroxybenzoic acid.

What is Salicylic Acid-d4 used for?

Salicylic Acid-d4 is supplied as a characterised reference material related to Salicylic acid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Salicylic Acid-d4 can I order?

We supply Salicylic Acid-d4 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Salicylic Acid-d4?

Yes. Every lot of Salicylic Acid-d4 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Salicylic Acid-d4 be shipped internationally?

Yes. Salicylic Acid-d4 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.