N-Demethyl Olanzapine D8

About N-Demethyl Olanzapine D8

N-Demethyl Olanzapine D8 is a stable isotope labelled analogue related to Olanzapine carrying the CAS registry number 786686-82-6. With the molecular formula C16H18N4S, it has a molar mass of 306.5 g/mol. The IUPAC name is 2-methyl-4-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine. It is also known as N-Desmethyl Olanzapine D8 or N-Desmethyl Olanzapine-d8.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Olanzapine and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Olanzapine

View every impurity, metabolite and intermediate we list for Olanzapine.

Olanzapine impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	N-Demethyl Olanzapine D8
Catalogue No.	VQ-034938
CAS Number	786686-82-6
IUPAC name	2-methyl-4-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Molecular formula	C₁₆H₁₈N₄S
Molecular weight	306.5 g/mol
Exact mass	306.1754
Grade	Reference Standard
HSN code	38229090
InChIKey	FHPIXVHJEIZKJW-COMRDEPKSA-N
SMILES	[2H]C1(C(N(C(C(N1)([2H])[2H])([2H])[2H])C2=NC3=CC=CC=C3NC4=C2C=C(S4)C)([2H])[2H])[2H]
PubChem CID	136232977

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 4
TPSA	67.9 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Demethyl Olanzapine D8?

The CAS Registry Number of N-Demethyl Olanzapine D8 is 786686-82-6. It is also known as N-Desmethyl Olanzapine D8, N-Desmethyl Olanzapine-d8, TMIH-0382.

What is the molecular formula and molecular weight of N-Demethyl Olanzapine D8?

N-Demethyl Olanzapine D8 has the molecular formula C16H18N4S and a molecular weight of 306.5 g/mol. Its IUPAC name is 2-methyl-4-(2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine.

What is N-Demethyl Olanzapine D8 used for?

N-Demethyl Olanzapine D8 is supplied as a characterised reference material related to Olanzapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Demethyl Olanzapine D8 can I order?

We supply N-Demethyl Olanzapine D8 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Demethyl Olanzapine D8?

Yes. Every lot of N-Demethyl Olanzapine D8 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Demethyl Olanzapine D8 be shipped internationally?

Yes. We export N-Demethyl Olanzapine D8 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.