Sertraline

About Sertraline

Sertraline is a high-purity reference standard of Sertraline carrying the CAS registry number 79617-96-2. Formula C17H17Cl2N, molecular weight 306.2 g/mol. Its systematic (IUPAC) name is (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine. It is also known as cis-(+)-sertraline or (1S,4S)-sertraline.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Sertraline, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Sertraline in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sertraline

View every impurity, metabolite and intermediate we list for Sertraline.

Sertraline impurities

Specifications & identifiers

Chemical identifiers
Product name	Sertraline
Catalogue No.	VQ-007752
CAS Number	79617-96-2
Other CAS	79559-97-0, 254731-40-3
IUPAC name	(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
Molecular formula	C₁₇H₁₇Cl₂N
Molecular weight	306.2 g/mol
Exact mass	305.0738
Grade	Reference Standard
HSN code	38229090
InChIKey	VGKDLMBJGBXTGI-SJCJKPOMSA-N
SMILES	CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl
PubChem CID	68617

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 1
TPSA	12 Å²
Synonyms	(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine, (1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine, cis-(+)-sertraline, (1S,4S)-sertraline, (+)-Sertraline, 1-Naphthalenamine, 1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-, (1S-cis)-, Altruline, Apo Sertraline, Gen Sertraline, Novo Sertraline, ratio Sertraline, Rhoxal sertraline

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P317, P330, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sertraline?

The CAS Registry Number of Sertraline is 79617-96-2. It is also known as (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine, (1S-cis)-1,2,3,4-Tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine, cis-(+)-sertraline.

What is the molecular formula and molecular weight of Sertraline?

Sertraline has the molecular formula C17H17Cl2N and a molecular weight of 306.2 g/mol. Its IUPAC name is (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine.

What is Sertraline used for?

Sertraline is supplied as a characterised reference material related to Sertraline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sertraline can I order?

We supply Sertraline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sertraline?

Yes. Every lot of Sertraline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sertraline be shipped internationally?

Yes. Sertraline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.