Piperaquine Impurity-G(Stage-II Freebase)

Name: Piperaquine Impurity-G(Stage-II Freebase)
Brand: Vaqora Chemicals
SKU: VQ-005538

About Piperaquine Impurity-G(Stage-II Freebase)

Listed under CAS 837-52-5, Piperaquine Impurity-G(Stage-II Freebase) is an impurity of Piperaquine available from Vaqora Chemicals. Formula C13H14ClN3, molecular weight 247.72 g/mol. The IUPAC name is 7-chloro-4-piperazin-1-ylquinoline. It is also known as 1-(7-Chloro-4-quinolyl)piperazine or 1-(7-Chloroquinolin-4-yl)piperazine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

This Piperaquine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Piperaquine Impurity-G(Stage-II Freebase) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Piperaquine

View every impurity, metabolite and intermediate we list for Piperaquine.

Piperaquine impurities

Specifications & identifiers

Chemical identifiers
Product name	Piperaquine Impurity-G(Stage-II Freebase)
Catalogue No.	VQ-005538
CAS Number	837-52-5
IUPAC name	7-chloro-4-piperazin-1-ylquinoline
Molecular formula	C₁₃H₁₄ClN₃
Molecular weight	247.72 g/mol
Exact mass	247.0876
Grade	Reference Standard
HSN code	38229090
InChIKey	DNXNPMDUDGUXOB-UHFFFAOYSA-N
SMILES	C1CN(CCN1)C2=C3C=CC(=CC3=NC=C2)Cl
PubChem CID	738389

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	1 / 3
TPSA	28.2 Å²
Synonyms	1-(7-Chloro-4-quinolyl)piperazine, 1-(7-Chloroquinolin-4-yl)piperazine, 4-(1-Piperazinyl)-7-chloroquinoline, 4-(7-Chloro-4-quinolyl)-piperazine, 7-Chloro-4-(piperazin-1-yl)quinoline, 7-Chloro-4-(1-piperazinyl)quinoline, Quinoline, 7-chloro-4-(1-piperazinyl)-, Chloroquinolinylpiperazine, 7-Chloro-4-piperazinoquinoline, 7-Chloro-4-piperazinylquinoline, 7-Chloro-4-piperazin-1-yl-quinoline, 7-chloro-4-piperazino-quinoline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Piperaquine Impurity-G(Stage-II Freebase)?

The CAS Registry Number of Piperaquine Impurity-G(Stage-II Freebase) is 837-52-5. It is also known as 1-(7-Chloro-4-quinolyl)piperazine, 1-(7-Chloroquinolin-4-yl)piperazine, 4-(1-Piperazinyl)-7-chloroquinoline.

What is the molecular formula and molecular weight of Piperaquine Impurity-G(Stage-II Freebase)?

Piperaquine Impurity-G(Stage-II Freebase) has the molecular formula C13H14ClN3 and a molecular weight of 247.72 g/mol. Its IUPAC name is 7-chloro-4-piperazin-1-ylquinoline.

What is Piperaquine Impurity-G(Stage-II Freebase) used for?

Piperaquine Impurity-G(Stage-II Freebase) is supplied as a characterised reference material related to Piperaquine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Piperaquine Impurity-G(Stage-II Freebase) can I order?

We supply Piperaquine Impurity-G(Stage-II Freebase) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Piperaquine Impurity-G(Stage-II Freebase)?

Yes. Every lot of Piperaquine Impurity-G(Stage-II Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Piperaquine Impurity-G(Stage-II Freebase) be shipped internationally?

Yes. Piperaquine Impurity-G(Stage-II Freebase) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.