Linaclotide

Name: Linaclotide
Brand: Vaqora Chemicals
SKU: VQ-031556

About Linaclotide

Listed under CAS 851199-59-2, Linaclotide is a high-purity reference standard of Linaclotide available from Vaqora Chemicals. With the molecular formula C59H79N15O21S6, it has a molar mass of 1526.8 g/mol. Alternative names: ASP-0456 and ASP 0456.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Linaclotide, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Linaclotide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Linaclotide

View every impurity, metabolite and intermediate we list for Linaclotide.

Linaclotide impurities

Specifications & identifiers

Chemical identifiers
Product name	Linaclotide
Catalogue No.	VQ-031556
CAS Number	851199-59-2
IUPAC name	(2S)-2-[[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo-18,19,35,36,48,49-hexathia-2,5,11,14,23,26,29,32,39,42,45,52-dodecazatetracyclo[22.22.4.216,33.07,11]dopentacontane-38-carbonyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Molecular formula	C₅₉H₇₉N₁₅O₂₁S₆
Molecular weight	1526.8 g/mol
Exact mass	1525.3899
Grade	Reference Standard
HSN code	38229090
InChIKey	KXGCNMMJRFDFNR-WDRJZQOASA-N
SMILES	C[C@H]1C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O)C(=O)N[C@@H](CSSC[C@@H](C(=O)N3)N)C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N1)CC(=O)N)CC6=CC=C(C=C6)O)CCC(=O)O
PubChem CID	16158208

Physical properties
Physical form	Solid
LogP (XLogP3)	-6.8
H-bond donors / acceptors	19 / 28
TPSA	726 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Linaclotide?

The CAS Registry Number of Linaclotide is 851199-59-2. It is also known as ASP-0456, ASP 0456, Linaclotide (JAN/USAN).

What is the molecular formula and molecular weight of Linaclotide?

Linaclotide has the molecular formula C59H79N15O21S6 and a molecular weight of 1526.8 g/mol.

What is Linaclotide used for?

Linaclotide is supplied as a characterised reference material related to Linaclotide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Linaclotide can I order?

We supply Linaclotide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Linaclotide?

Yes. Every lot of Linaclotide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Linaclotide be shipped internationally?

Yes. Linaclotide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.