1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H… 865774-26-1

Name: 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine
Brand: Vaqora Chemicals
SKU: VQ-045233

About 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine

1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine (CAS 865774-26-1) is an impurity of Nirogacestat offered by Vaqora Chemicals. The compound has the formula C12H24N4, corresponding to a molecular weight of 224.35 g/mol. Systematically, it is named 1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-amine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Nirogacestat, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nirogacestat

View every impurity, metabolite and intermediate we list for Nirogacestat.

Nirogacestat impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine
Catalogue No.	VQ-045233
CAS Number	865774-26-1
IUPAC name	1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-amine
Molecular formula	C₁₂H₂₄N₄
Molecular weight	224.35 g/mol
Exact mass	224.2001
Grade	Reference Standard
HSN code	38229090
InChIKey	MXGFJOMENBCJIE-UHFFFAOYSA-N
SMILES	CC(C)(C)CNCC(C)(C)N1C=C(N=C1)N
PubChem CID	67163806

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	2 / 3
TPSA	55.9 Å²
Synonyms	1H-Imidazole-1-ethanamine, 4-amino-N-(2,2-dimethylpropyl)-beta,beta-dimethyl-, 1-{1-[(2,2-dimethylpropyl)amino]-2-methylpropan-2-yl}-1H-imidazol-4-amine, 4-Amino-1-[2-methyl-1-(neopentylamino)-2-propyl]imidazole, 1H-Imidazole-1-ethanamine, 4-amino-N-(2,2-dimethylpropyl)-,-dimethyl-, 1-[2-(2,2-dimethyl-propylamino)-1,1-dimethyl-ethyl]-1H-imidazol-4-ylamine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine?

The CAS Registry Number of 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine is 865774-26-1. It is also known as 1H-Imidazole-1-ethanamine, 4-amino-N-(2,2-dimethylpropyl)-beta,beta-dimethyl-, 1-{1-[(2,2-dimethylpropyl)amino]-2-methylpropan-2-yl}-1H-imidazol-4-amine, 4-Amino-1-[2-methyl-1-(neopentylamino)-2-propyl]imidazole.

What is the molecular formula and molecular weight of 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine?

1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine has the molecular formula C12H24N4 and a molecular weight of 224.35 g/mol. Its IUPAC name is 1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-amine.

What is 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine used for?

1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine is supplied as a characterised reference material related to Nirogacestat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine can I order?

We supply 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine?

Yes. Every lot of 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine be shipped internationally?

Yes. We export 1-(2-Methyl-1-(neopentylamino)propan-2-yl)-1H-imidazol-4-amine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.