Trandolapril EP Impurity E

About Trandolapril EP Impurity E

Trandolapril EP Impurity E is a pharmacopeial impurity of Trandolapril carrying the CAS registry number 87679-71-8. With the molecular formula C22H30N2O5, it has a molar mass of 402.5 g/mol. Alternative names: Trandolapril - Impurity E (Freebase) and Trandolaprilate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Trandolapril impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Trandolapril EP Impurity E is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Trandolapril

View every impurity, metabolite and intermediate we list for Trandolapril.

Trandolapril impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Trandolapril EP Impurity E
Catalogue No.	VQ-028476
CAS Number	87679-71-8
IUPAC name	(2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
Molecular formula	C₂₂H₃₀N₂O₅
Molecular weight	402.5 g/mol
Exact mass	402.2155
Grade	Reference Standard
HSN code	38229090
InChIKey	AHYHTSYNOHNUSH-HXFGRODQSA-N
SMILES	C[C@@H](C(=O)N1[C@H]2CCCC[C@@H]2C[C@H]1C(=O)O)N[C@@H](CCC3=CC=CC=C3)C(=O)O
PubChem CID	5464097

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	3 / 6
TPSA	107 Å²
Synonyms	Trandolapril - Impurity E (Freebase), Trandolaprilate, trandolapril diacid, Trandolapril impurity E, EX-A4862

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Trandolapril EP Impurity E?

The CAS Registry Number of Trandolapril EP Impurity E is 87679-71-8. It is also known as Trandolapril - Impurity E (Freebase), Trandolaprilate, trandolapril diacid.

What is the molecular formula and molecular weight of Trandolapril EP Impurity E?

Trandolapril EP Impurity E has the molecular formula C22H30N2O5 and a molecular weight of 402.5 g/mol. Its IUPAC name is (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid.

What is Trandolapril EP Impurity E used for?

Trandolapril EP Impurity E is supplied as a characterised reference material related to Trandolapril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Trandolapril EP Impurity E can I order?

We supply Trandolapril EP Impurity E in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Trandolapril EP Impurity E?

Yes. Every lot of Trandolapril EP Impurity E is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Trandolapril EP Impurity E be shipped internationally?

Yes. Trandolapril EP Impurity E is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.