(R)-Sitagliptin Methyl-Ester Impurity

Name: (R)-Sitagliptin Methyl-Ester Impurity
Brand: Vaqora Chemicals
SKU: VQ-023763

About (R)-Sitagliptin Methyl-Ester Impurity

Vaqora Chemicals supplies (R)-Sitagliptin Methyl-Ester Impurity, an impurity of Sitagliptin registered under CAS number 881995-69-3. Formula C11H12F3NO2, molecular weight 247.21 g/mol. The IUPAC name is methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate. It is also known as (R)-Sitagliptin methyl ester.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-Sitagliptin Methyl-Ester Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Sitagliptin Methyl-Ester Impurity
Catalogue No.	VQ-023763
CAS Number	881995-69-3
IUPAC name	methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate
Molecular formula	C₁₁H₁₂F₃NO₂
Molecular weight	247.21 g/mol
Exact mass	247.082
Grade	Reference Standard
HSN code	38229090
InChIKey	AWFWTEYDIPQVSG-SSDOTTSWSA-N
SMILES	COC(=O)C[C@@H](CC1=CC(=C(C=C1F)F)F)N
PubChem CID	49784072

Physical properties
Physical form	Solid
LogP (XLogP3)	1.4
H-bond donors / acceptors	1 / 6
TPSA	52.3 Å²
Synonyms	(R)-Sitagliptin Methyl-Ester Impurity (Free Base), (r)-methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate, Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)-, (R)-Sitagliptin methyl ester, (3R)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate, (r)-methyl3-amino-4-(2,4,5-trifluorophenyl)butanoate, Methyl(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate, Methyl (betaR)-beta-amino-2,4,5-trifluorobenzenebutanoate, Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(Br), Benzenebutanoic acid, beta-amino-2,4,5-trifluoro-, methyl ester, (betaR)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Sitagliptin Methyl-Ester Impurity?

The CAS Registry Number of (R)-Sitagliptin Methyl-Ester Impurity is 881995-69-3. It is also known as (R)-Sitagliptin Methyl-Ester Impurity (Free Base), (r)-methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate, Benzenebutanoicacid,b-aMino-2,4,5-trifluoro-,Methylester,(bR)-.

What is the molecular formula and molecular weight of (R)-Sitagliptin Methyl-Ester Impurity?

(R)-Sitagliptin Methyl-Ester Impurity has the molecular formula C11H12F3NO2 and a molecular weight of 247.21 g/mol. Its IUPAC name is methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate.

What is (R)-Sitagliptin Methyl-Ester Impurity used for?

(R)-Sitagliptin Methyl-Ester Impurity is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Sitagliptin Methyl-Ester Impurity can I order?

We supply (R)-Sitagliptin Methyl-Ester Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Sitagliptin Methyl-Ester Impurity?

Yes. Every lot of (R)-Sitagliptin Methyl-Ester Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Sitagliptin Methyl-Ester Impurity be shipped internationally?

Yes. We export (R)-Sitagliptin Methyl-Ester Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.