Axitinib Tetrahydro-2H-pyran

Name: Axitinib Tetrahydro-2H-pyran
Brand: Vaqora Chemicals
SKU: VQ-024459

About Axitinib Tetrahydro-2H-pyran

Axitinib Tetrahydro-2H-pyran (CAS 885126-35-2) is an impurity of Axitinib offered by Vaqora Chemicals. Its molecular formula is C27H26N4O2S and its molecular weight is 470.6 g/mol. Its systematic (IUPAC) name is N-methyl-2-[1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-yl]sulfanylbenzamide.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Axitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Axitinib Tetrahydro-2H-pyran in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Axitinib

View every impurity, metabolite and intermediate we list for Axitinib.

Axitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Axitinib Tetrahydro-2H-pyran
Catalogue No.	VQ-024459
CAS Number	885126-35-2
IUPAC name	N-methyl-2-[1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-yl]sulfanylbenzamide
Molecular formula	C₂₇H₂₆N₄O₂S
Molecular weight	470.6 g/mol
Exact mass	470.1776
Grade	Reference Standard
HSN code	38229090
InChIKey	ICISLZFPVJBDJL-NTCAYCPXSA-N
SMILES	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3C4CCCCO4)/C=C/C5=CC=CC=N5
PubChem CID	16726368

Physical properties
Physical form	Solid
LogP (XLogP3)	5
H-bond donors / acceptors	1 / 5
TPSA	94.3 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P270, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Axitinib Tetrahydro-2H-pyran?

The CAS Registry Number of Axitinib Tetrahydro-2H-pyran is 885126-35-2. It is also known as N-methyl-2-(1-(oxan-2-yl)-3-((E)-2-pyridin-2-ylethenyl)indazol-6-yl)sulfanylbenzamide.

What is the molecular formula and molecular weight of Axitinib Tetrahydro-2H-pyran?

Axitinib Tetrahydro-2H-pyran has the molecular formula C27H26N4O2S and a molecular weight of 470.6 g/mol. Its IUPAC name is N-methyl-2-[1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-yl]sulfanylbenzamide.

What is Axitinib Tetrahydro-2H-pyran used for?

Axitinib Tetrahydro-2H-pyran is supplied as a characterised reference material related to Axitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Axitinib Tetrahydro-2H-pyran can I order?

We supply Axitinib Tetrahydro-2H-pyran in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Axitinib Tetrahydro-2H-pyran?

Yes. Every lot of Axitinib Tetrahydro-2H-pyran is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Axitinib Tetrahydro-2H-pyran be shipped internationally?

Yes. Axitinib Tetrahydro-2H-pyran is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.