(E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2… 886230-76-8

Name: (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine
Brand: Vaqora Chemicals
SKU: VQ-035874

About (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine

(E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine is an impurity of Axitinib carrying the CAS registry number 886230-76-8. The compound has the formula C19H20N4O, corresponding to a molecular weight of 320.4 g/mol. Its systematic (IUPAC) name is 1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-amine. Alternative names: Axitinib Pyran.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Axitinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Axitinib

View every impurity, metabolite and intermediate we list for Axitinib.

Axitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine
Catalogue No.	VQ-035874
CAS Number	886230-76-8
IUPAC name	1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-amine
Molecular formula	C₁₉H₂₀N₄O
Molecular weight	320.4 g/mol
Exact mass	320.1637
Grade	Reference Standard
HSN code	38229090
InChIKey	NSPUYMWXWXSVAJ-CSKARUKUSA-N
SMILES	C1CCOC(C1)N2C3=C(C=CC(=C3)N)C(=N2)/C=C/C4=CC=CC=N4
PubChem CID	58636017

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 4
TPSA	66 Å²
Synonyms	3-[(1E)-2-(2-Pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine, 3-((1E)-2-(2-Pyridinyl)ethenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine, Axitinib Pyran, 3-(2-Pyridin-2-yl-vinyl)-1-(tetrahydro-pyran-2-yl)-1H-indazol-6-ylamine, 1H-Indazol-6-amine, 3-[(1E)-2-(2-pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-, 3-[2-(2-Pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine?

The CAS Registry Number of (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine is 886230-76-8. It is also known as 3-[(1E)-2-(2-Pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine, 3-((1E)-2-(2-Pyridinyl)ethenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine, Axitinib Pyran.

What is the molecular formula and molecular weight of (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine?

(E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine has the molecular formula C19H20N4O and a molecular weight of 320.4 g/mol. Its IUPAC name is 1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazol-6-amine.

What is (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine used for?

(E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine is supplied as a characterised reference material related to Axitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine can I order?

We supply (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine?

Yes. Every lot of (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine be shipped internationally?

Yes. We export (E)-3-(2-(Pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.