N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methy… 90357-51-0

Name: N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
Brand: Vaqora Chemicals
SKU: VQ-021825

About N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide is an impurity of Bicalutamide carrying the CAS registry number 90357-51-0. Its molecular formula is C12H9F3N2O2 and its molecular weight is 270.21 g/mol. Its systematic (IUPAC) name is N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide. Alternative names: Bicalutamide Intermediate (epoxy).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Bicalutamide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bicalutamide

View every impurity, metabolite and intermediate we list for Bicalutamide.

Bicalutamide impurities

Specifications & identifiers

Chemical identifiers
Product name	N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
Catalogue No.	VQ-021825
CAS Number	90357-51-0
IUPAC name	N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
Molecular formula	C₁₂H₉F₃N₂O₂
Molecular weight	270.21 g/mol
Exact mass	270.0616
Grade	Reference Standard
HSN code	38229090
InChIKey	UQUQTWDUTIAAAY-UHFFFAOYSA-N
SMILES	CC1(CO1)C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F
PubChem CID	10149314

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	1 / 6
TPSA	65.4 Å²
Synonyms	N-(4-cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide, N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide, Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-, 4-Cyano-N-(2,3-epoxy-2-methylpropionyl)-3-trifluoromethylaniline, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxirane-2-carboxamide, Bicalutamide Intermediate (epoxy), N-[4-cyano-3-trifluoromethylphenyl]-2-methyloxiranecaboxamide, 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethyl-phenyl)-amide, 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide?

The CAS Registry Number of N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide is 90357-51-0. It is also known as N-(4-cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide, N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide, Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-.

What is the molecular formula and molecular weight of N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide?

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide has the molecular formula C12H9F3N2O2 and a molecular weight of 270.21 g/mol. Its IUPAC name is N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide.

What is N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide used for?

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide is supplied as a characterised reference material related to Bicalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide can I order?

We supply N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide?

Yes. Every lot of N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide be shipped internationally?

Yes. N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.