Betamethasone Acetate EP Impurity D

About Betamethasone Acetate EP Impurity D

Betamethasone Acetate EP Impurity D is a pharmacopeial impurity of Betamethasone carrying the CAS registry number 912-38-9. The compound has the formula C24H30O6, corresponding to a molecular weight of 414.5 g/mol. Alternative names: Betamethasone Acetate Impurity D and Betamethasone Acetate Related Compound D.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Betamethasone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Betamethasone Acetate EP Impurity D in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Betamethasone

View every impurity, metabolite and intermediate we list for Betamethasone.

Betamethasone impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Betamethasone Acetate EP Impurity D
Catalogue No.	VQ-020944
CAS Number	912-38-9
IUPAC name	[2-[(1S,2S,10S,11S,13S,14R,15S,17S)-14-hydroxy-2,13,15-trimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-14-yl]-2-oxoethyl] acetate
Molecular formula	C₂₄H₃₀O₆
Molecular weight	414.5 g/mol
Exact mass	414.2042
Grade	Reference Standard
HSN code	38229090
InChIKey	MONKXVNQUJNHLQ-LGLNQOIUSA-N
SMILES	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]35[C@@H](O5)C[C@@]2([C@]1(C(=O)COC(=O)C)O)C)C
PubChem CID	101904

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 6
TPSA	93.2 Å²
Synonyms	Betamethasone Acetate Impurity D, Betamethasone Acetate Related Compound D, Betamethasone Acetate - Impurity D, 9b,11b-Epoxy-17,21-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione 21-Acetate, 9beta,11beta-Epoxy-17,21-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-acetate, 9,11beta-Epoxy-17-hydroxy-16beta-methyl-3,20-dioxo-9beta-pregna-1,4-diene-21-yl acetate, 9,11beta-Epoxy-17-hydroxy-16beta-methyl-3,20-dioxo-9beta-pregna-1,4-diene 21-Acetate, 17-Hydroxy-16-methyl-3,20-dioxo-9,11-epoxypregna-1,4-dien-21-yl acetate, 17-Hydroxy-16beta-methyl-3,20-dioxo-9beta,11beta-9,11-epoxypregna-1,4-dien-21-yl acetate

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P319, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Betamethasone Acetate EP Impurity D?

The CAS Registry Number of Betamethasone Acetate EP Impurity D is 912-38-9. It is also known as Betamethasone Acetate Impurity D, Betamethasone Acetate Related Compound D, Betamethasone Acetate - Impurity D.

What is the molecular formula and molecular weight of Betamethasone Acetate EP Impurity D?

Betamethasone Acetate EP Impurity D has the molecular formula C24H30O6 and a molecular weight of 414.5 g/mol. Its IUPAC name is [2-[(1S,2S,10S,11S,13S,14R,15S,17S)-14-hydroxy-2,13,15-trimethyl-5-oxo-18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadeca-3,6-dien-14-yl]-2-oxoethyl] acetate.

What is Betamethasone Acetate EP Impurity D used for?

Betamethasone Acetate EP Impurity D is supplied as a characterised reference material related to Betamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Betamethasone Acetate EP Impurity D can I order?

We supply Betamethasone Acetate EP Impurity D in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Betamethasone Acetate EP Impurity D?

Yes. Every lot of Betamethasone Acetate EP Impurity D is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Betamethasone Acetate EP Impurity D be shipped internationally?

Yes. Betamethasone Acetate EP Impurity D is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.