5,6-Dichloropyrimidine-4-carboxylic Acid

Name: 5,6-Dichloropyrimidine-4-carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-042633

About 5,6-Dichloropyrimidine-4-carboxylic Acid

Listed under CAS 914916-97-5, 5,6-Dichloropyrimidine-4-carboxylic Acid is an impurity of Regorafenib available from Vaqora Chemicals. Its molecular formula is C5H2Cl2N2O2 and its molecular weight is 192.98 g/mol. It is also known as 5,6-Dichloro-4-pyrimidinecarboxylic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Regorafenib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 5,6-Dichloropyrimidine-4-carboxylic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Regorafenib

View every impurity, metabolite and intermediate we list for Regorafenib.

Regorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	5,6-Dichloropyrimidine-4-carboxylic Acid
Catalogue No.	VQ-042633
CAS Number	914916-97-5
IUPAC name	5,6-dichloropyrimidine-4-carboxylic acid
Molecular formula	C₅H₂Cl₂N₂O₂
Molecular weight	192.98 g/mol
Exact mass	191.9493
Grade	Reference Standard
HSN code	38229090
InChIKey	MEATVPFVKDQTSD-UHFFFAOYSA-N
SMILES	C1=NC(=C(C(=N1)Cl)Cl)C(=O)O
PubChem CID	70700527

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	1 / 4
TPSA	63.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5,6-Dichloropyrimidine-4-carboxylic Acid?

The CAS Registry Number of 5,6-Dichloropyrimidine-4-carboxylic Acid is 914916-97-5. It is also known as 5,6-Dichloro-4-pyrimidinecarboxylic acid.

What is the molecular formula and molecular weight of 5,6-Dichloropyrimidine-4-carboxylic Acid?

5,6-Dichloropyrimidine-4-carboxylic Acid has the molecular formula C5H2Cl2N2O2 and a molecular weight of 192.98 g/mol. Its IUPAC name is 5,6-dichloropyrimidine-4-carboxylic acid.

What is 5,6-Dichloropyrimidine-4-carboxylic Acid used for?

5,6-Dichloropyrimidine-4-carboxylic Acid is supplied as a characterised reference material related to Regorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5,6-Dichloropyrimidine-4-carboxylic Acid can I order?

We supply 5,6-Dichloropyrimidine-4-carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5,6-Dichloropyrimidine-4-carboxylic Acid?

Yes. Every lot of 5,6-Dichloropyrimidine-4-carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5,6-Dichloropyrimidine-4-carboxylic Acid be shipped internationally?

Yes. 5,6-Dichloropyrimidine-4-carboxylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.