Nilotinib Hydrochloride

Name: Nilotinib Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007613

About Nilotinib Hydrochloride

Vaqora Chemicals supplies Nilotinib Hydrochloride, a high-purity reference standard of Nilotinib registered under CAS number 923288-95-3. Its molecular formula is C28H23ClF3N7O and its molecular weight is 566.0 g/mol. Common synonyms include Nilotinib hydrochloride anhydrous and Nilotinib HCl.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Nilotinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Nilotinib Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nilotinib

View every impurity, metabolite and intermediate we list for Nilotinib.

Nilotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Nilotinib Hydrochloride
Catalogue No.	VQ-007613
CAS Number	923288-95-3
IUPAC name	4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide;hydrochloride
Molecular formula	C₂₈H₂₃ClF₃N₇O
Molecular weight	566 g/mol
Exact mass	565.1605
Grade	Reference Standard
HSN code	38229090
InChIKey	VTGGYCCJUPYZSX-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.Cl
PubChem CID	16006490

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 9
TPSA	97.6 Å²
Synonyms	Nilotinib hydrochloride anhydrous, Nilotinib HCl, Nilotinib (hydrochloride), Nilotinib (as hydrochloride), AMN-107 HCl, AMN 107 hydrochloride, C28H23ClF3N7O, Nilotinib HCl monohydrate - Bio-X trade mark

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P264 + P265, P273, P280, P302 + P352, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nilotinib Hydrochloride?

The CAS Registry Number of Nilotinib Hydrochloride is 923288-95-3. It is also known as Nilotinib hydrochloride anhydrous, Nilotinib HCl, Nilotinib (hydrochloride).

What is the molecular formula and molecular weight of Nilotinib Hydrochloride?

Nilotinib Hydrochloride has the molecular formula C28H23ClF3N7O and a molecular weight of 566 g/mol.

What is Nilotinib Hydrochloride used for?

Nilotinib Hydrochloride is supplied as a characterised reference material related to Nilotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nilotinib Hydrochloride can I order?

We supply Nilotinib Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nilotinib Hydrochloride?

Yes. Every lot of Nilotinib Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nilotinib Hydrochloride be shipped internationally?

Yes. Nilotinib Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.