Cobimetinib R Isomer

Name: Cobimetinib R Isomer
Brand: Vaqora Chemicals
SKU: VQ-029921

About Cobimetinib R Isomer

Listed under CAS 934660-94-3, Cobimetinib R Isomer is an impurity of Cobimetinib available from Vaqora Chemicals. Its molecular formula is C21H21F3IN3O2 and its molecular weight is 531.3 g/mol. Systematically, it is named [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl]methanone. Alternative names: Cobimetinib (R-enantiomer) and (R)-XL 518.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Cobimetinib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Cobimetinib R Isomer in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cobimetinib

View every impurity, metabolite and intermediate we list for Cobimetinib.

Cobimetinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Cobimetinib R Isomer
Catalogue No.	VQ-029921
CAS Number	934660-94-3
IUPAC name	[3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl]methanone
Molecular formula	C₂₁H₂₁F₃IN₃O₂
Molecular weight	531.3 g/mol
Exact mass	531.0631
Grade	Reference Standard
HSN code	38229090
InChIKey	BSMCAPRUBJMWDF-QGZVFWFLSA-N
SMILES	C1CCN[C@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
PubChem CID	16222097

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	3 / 7
TPSA	64.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cobimetinib R Isomer?

The CAS Registry Number of Cobimetinib R Isomer is 934660-94-3. It is also known as Cobimetinib (R-enantiomer), (R)-XL 518, Cobimetinib R-enantiomer.

What is the molecular formula and molecular weight of Cobimetinib R Isomer?

Cobimetinib R Isomer has the molecular formula C21H21F3IN3O2 and a molecular weight of 531.3 g/mol. Its IUPAC name is [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2R)-piperidin-2-yl]azetidin-1-yl]methanone.

What is Cobimetinib R Isomer used for?

Cobimetinib R Isomer is supplied as a characterised reference material related to Cobimetinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cobimetinib R Isomer can I order?

We supply Cobimetinib R Isomer in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cobimetinib R Isomer?

Yes. Every lot of Cobimetinib R Isomer is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cobimetinib R Isomer be shipped internationally?

Yes. We export Cobimetinib R Isomer worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.