(S)-Ibrutinib

Name: (S)-Ibrutinib
Brand: Vaqora Chemicals
SKU: VQ-004280

About (S)-Ibrutinib

(S)-Ibrutinib is an impurity of Ibrutinib carrying the CAS registry number 936563-97-2. With the molecular formula C25H24N6O2, it has a molar mass of 440.5 g/mol. Systematically, it is named 1-[(3S)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one. Alternative names: Ibrutinib, (S)- and Ibrutinib (S)-Isomer.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Ibrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (S)-Ibrutinib in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ibrutinib

View every impurity, metabolite and intermediate we list for Ibrutinib.

Ibrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-Ibrutinib
Catalogue No.	VQ-004280
CAS Number	936563-97-2
IUPAC name	1-[(3S)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one
Molecular formula	C₂₅H₂₄N₆O₂
Molecular weight	440.5 g/mol
Exact mass	440.1961
Grade	Reference Standard
HSN code	38229090
InChIKey	XYFPWWZEPKGCCK-SFHVURJKSA-N
SMILES	C=CC(=O)N1CCC[C@@H](C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
PubChem CID	24821023

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	1 / 6
TPSA	99.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-Ibrutinib?

The CAS Registry Number of (S)-Ibrutinib is 936563-97-2. It is also known as Ibrutinib, (S)-, Ibrutinib (S)-Isomer, (S)-1-(3-(4-amino-3-(4-phenoxyphenyl).

What is the molecular formula and molecular weight of (S)-Ibrutinib?

(S)-Ibrutinib has the molecular formula C25H24N6O2 and a molecular weight of 440.5 g/mol. Its IUPAC name is 1-[(3S)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one.

What is (S)-Ibrutinib used for?

(S)-Ibrutinib is supplied as a characterised reference material related to Ibrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-Ibrutinib can I order?

We supply (S)-Ibrutinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-Ibrutinib?

Yes. Every lot of (S)-Ibrutinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-Ibrutinib be shipped internationally?

Yes. We export (S)-Ibrutinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.