2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2… 943126-72-5

Name: 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone
Brand: Vaqora Chemicals
SKU: VQ-032078

About 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone

Listed under CAS 943126-72-5, 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone is an impurity of Nebivolol available from Vaqora Chemicals. With the molecular formula C11H10ClFO2, it has a molar mass of 228.65 g/mol. Alternative names: 2-chloro-1-(6-fluorochroman-2-yl)ethanone and 2-Chloro-1-(6-fluorochroman-2-yl)ethan-1-one.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Nebivolol, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone
Catalogue No.	VQ-032078
CAS Number	943126-72-5
IUPAC name	2-chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone
Molecular formula	C₁₁H₁₀ClFO₂
Molecular weight	228.65 g/mol
Exact mass	228.0353
Grade	Reference Standard
HSN code	38229090
InChIKey	JOIVVMUMDLHKRF-UHFFFAOYSA-N
SMILES	C1CC2=C(C=CC(=C2)F)OC1C(=O)CCl
PubChem CID	16755387

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 3
TPSA	26.3 Å²
Synonyms	2-chloro-1-(6-fluorochroman-2-yl)ethanone, 2-Chloro-1-(6-fluorochroman-2-yl)ethan-1-one, Ethanone, 2-chloro-1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-, 2-Chloro-1-(6-fluoro-3,4-dihydro-1-benzopyran-2-yl)ethanone, 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)ethanone, 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)ethan-1-one

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone?

The CAS Registry Number of 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone is 943126-72-5. It is also known as 2-chloro-1-(6-fluorochroman-2-yl)ethanone, 2-Chloro-1-(6-fluorochroman-2-yl)ethan-1-one, Ethanone, 2-chloro-1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-.

What is the molecular formula and molecular weight of 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone?

2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone has the molecular formula C11H10ClFO2 and a molecular weight of 228.65 g/mol. Its IUPAC name is 2-chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone.

What is 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone used for?

2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone can I order?

We supply 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone?

Yes. Every lot of 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone be shipped internationally?

Yes. 2-Chloro-1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.