Salmeterol EP Impurity B

About Salmeterol EP Impurity B

Salmeterol EP Impurity B is a pharmacopeial impurity of Salmeterol carrying the CAS registry number 94749-02-7. Its molecular formula is C23H33NO4 and its molecular weight is 387.5 g/mol. Systematically, it is named 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(2-phenylethoxy)hexylamino]ethyl]phenol. It is also known as Salmeterol - Impurity B or Des(phenylbutoxy)phenylethoxy salmeterol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Salmeterol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Pharmacopeial method verification
Impurity profiling
QC release testing
ANDA / DMF filings

Industries

Related to Salmeterol

View every impurity, metabolite and intermediate we list for Salmeterol.

Salmeterol impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Salmeterol EP Impurity B
Catalogue No.	VQ-023735
CAS Number	94749-02-7
IUPAC name	2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(2-phenylethoxy)hexylamino]ethyl]phenol
Molecular formula	C₂₃H₃₃NO₄
Molecular weight	387.5 g/mol
Exact mass	387.241
Grade	Reference Standard
HSN code	38229090
InChIKey	SFLNGSUKAXWYTL-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)CCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
PubChem CID	13375575

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	4 / 5
TPSA	82 Å²
Synonyms	Salmeterol - Impurity B, Des(phenylbutoxy)phenylethoxy salmeterol, o-Des(phenylbutyl)-o-phenylethyl salmeterol, (1RS)-1-(4-Hydroxy-3-(hydroxymethyl)phenyl)-2-((6-(2-phenylethoxy)hexyl)amino)ethanol, 1,3-Benzenedimethanol, 4-hydroxy-alpha1-(((6-(2-phenylethoxy)hexyl)amino)methyl)-, (1RS)-1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-2-[[6-(2-phenylethoxy)hexyl]amino]ethanol, Salmeterol xinafoate specified impurity B, 4-hydroxy-alpha1-[[[6-(2-phenylethoxy)hexyl]amino]methyl]-1,3-benzenedimethanol, 4-(1-Hydroxy-2-((6-phenethoxyhexyl)amino)ethyl)-2-(hydroxymethyl)phenol, Des(phenylbutoxy)phenylethoxy salmeterol, (+/-)-, 2-(Hydroxymethyl)-4-(1-hydroxy-2-{[6-(2-phenylethoxy)hexyl]amino}ethyl)phenol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Salmeterol EP Impurity B?

The CAS Registry Number of Salmeterol EP Impurity B is 94749-02-7. It is also known as Salmeterol - Impurity B, Des(phenylbutoxy)phenylethoxy salmeterol, o-Des(phenylbutyl)-o-phenylethyl salmeterol.

What is the molecular formula and molecular weight of Salmeterol EP Impurity B?

Salmeterol EP Impurity B has the molecular formula C23H33NO4 and a molecular weight of 387.5 g/mol. Its IUPAC name is 2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(2-phenylethoxy)hexylamino]ethyl]phenol.

What is Salmeterol EP Impurity B used for?

Salmeterol EP Impurity B is supplied as a characterised reference material related to Salmeterol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Salmeterol EP Impurity B can I order?

We supply Salmeterol EP Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Salmeterol EP Impurity B?

Yes. Every lot of Salmeterol EP Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Salmeterol EP Impurity B be shipped internationally?

Yes. Salmeterol EP Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.