Celecoxib N-des(benzenesulfonamide)

Name: Celecoxib N-des(benzenesulfonamide)
Brand: Vaqora Chemicals
SKU: VQ-029721

About Celecoxib N-des(benzenesulfonamide)

Listed under CAS 948293-46-7, Celecoxib N-des(benzenesulfonamide) is an impurity of Celecoxib available from Vaqora Chemicals. With the molecular formula C11H9F3N2, it has a molar mass of 226.2 g/mol. Its systematic (IUPAC) name is 3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazole. Common synonyms include Desaryl Celecoxib and 3-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

This Celecoxib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Celecoxib N-des(benzenesulfonamide) in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Celecoxib

View every impurity, metabolite and intermediate we list for Celecoxib.

Celecoxib impurities

Specifications & identifiers

Chemical identifiers
Product name	Celecoxib N-des(benzenesulfonamide)
Catalogue No.	VQ-029721
CAS Number	948293-46-7
IUPAC name	3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazole
Molecular formula	C₁₁H₉F₃N₂
Molecular weight	226.2 g/mol
Exact mass	226.0718
Grade	Reference Standard
HSN code	38229090
InChIKey	NQEFIPVOJGJVRG-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)C2=NNC(=C2)C(F)(F)F
PubChem CID	4166967

Physical properties
Physical form	Solid
LogP (XLogP3)	3.2
H-bond donors / acceptors	1 / 4
TPSA	28.7 Å²
Synonyms	Desaryl Celecoxib, 5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole, 1H-Pyrazole, 5-(4-methylphenyl)-3-(trifluoromethyl)-, 5-(4-methylphenyl)-3-trifluoromethyl-1h-pyrazole, 3-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole, 3-(4-methylphenyl)-5-(trifluoromethyl)pyrazole, 5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazole, 3-(Trifluoromethyl)-5-p-tolyl-1H-pyrazole, 3-trifluoromethyl-5-(p-tolyl)-1h-pyrazole, Celecoxib-010-1, 1H-Pyrazole, 3-(4-methylphenyl)-5-(trifluoromethyl)-, 3-p-tolyl-5-(trifluormethyl)-1H-pyrazole

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Celecoxib N-des(benzenesulfonamide)?

The CAS Registry Number of Celecoxib N-des(benzenesulfonamide) is 948293-46-7. It is also known as Desaryl Celecoxib, 5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole, 1H-Pyrazole, 5-(4-methylphenyl)-3-(trifluoromethyl)-.

What is the molecular formula and molecular weight of Celecoxib N-des(benzenesulfonamide)?

Celecoxib N-des(benzenesulfonamide) has the molecular formula C11H9F3N2 and a molecular weight of 226.2 g/mol. Its IUPAC name is 3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazole.

What is Celecoxib N-des(benzenesulfonamide) used for?

Celecoxib N-des(benzenesulfonamide) is supplied as a characterised reference material related to Celecoxib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Celecoxib N-des(benzenesulfonamide) can I order?

We supply Celecoxib N-des(benzenesulfonamide) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Celecoxib N-des(benzenesulfonamide)?

Yes. Every lot of Celecoxib N-des(benzenesulfonamide) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Celecoxib N-des(benzenesulfonamide) be shipped internationally?

Yes. Celecoxib N-des(benzenesulfonamide) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.