Baricitinib Diamine Impurity

Name: Baricitinib Diamine Impurity
Brand: Vaqora Chemicals
SKU: VQ-004480

About Baricitinib Diamine Impurity

Listed under CAS 952518-97-7, Baricitinib Diamine Impurity is an impurity of Baricitinib available from Vaqora Chemicals. The compound has the formula C9H7N5, corresponding to a molecular weight of 185.19 g/mol. Its systematic (IUPAC) name is 4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine. Common synonyms include Ruxolitinib Diamine Impurity and Ruxolitinib impurity-1.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Baricitinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Baricitinib Diamine Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Baricitinib

View every impurity, metabolite and intermediate we list for Baricitinib.

Baricitinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Baricitinib Diamine Impurity
Catalogue No.	VQ-004480
CAS Number	952518-97-7
IUPAC name	4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine
Molecular formula	C₉H₇N₅
Molecular weight	185.19 g/mol
Exact mass	185.0701
Grade	Reference Standard
HSN code	38229090
InChIKey	FKZDJXVOWLWXHB-UHFFFAOYSA-N
SMILES	C1=CNC2=NC=NC(=C21)C3=CNN=C3
PubChem CID	24963938

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	2 / 3
TPSA	70.3 Å²
Synonyms	Ruxolitinib Diamine Impurity, 4-{7H-Pyrrolo[2,3-d]pyrimidin-4-yl-1H-pyrazole, 4-(7H-Pyrrolo(2,3-d)pyrimidin-4-yl-1H-pyrazole, 4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazole, Ruxolitinib impurity-1, 4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole, Ruxolitinib Impurity G, 7H-Pyrrolo[2,3, 7H-Pyrrolo[2,3-d]pyrimidine, 4-(1H-pyrazol-4-yl)-, 4-(4-pyrazolyl)pyrrolo[2,3-d]pyrimidine, 4-(4-pyrazolyl)-7H-pyrrolo[2,3-d]pyrimidine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Baricitinib Diamine Impurity?

The CAS Registry Number of Baricitinib Diamine Impurity is 952518-97-7. It is also known as Ruxolitinib Diamine Impurity, 4-{7H-Pyrrolo[2,3-d]pyrimidin-4-yl-1H-pyrazole, 4-(7H-Pyrrolo(2,3-d)pyrimidin-4-yl-1H-pyrazole.

What is the molecular formula and molecular weight of Baricitinib Diamine Impurity?

Baricitinib Diamine Impurity has the molecular formula C9H7N5 and a molecular weight of 185.19 g/mol. Its IUPAC name is 4-(1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine.

What is Baricitinib Diamine Impurity used for?

Baricitinib Diamine Impurity is supplied as a characterised reference material related to Baricitinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Baricitinib Diamine Impurity can I order?

We supply Baricitinib Diamine Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Baricitinib Diamine Impurity?

Yes. Every lot of Baricitinib Diamine Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Baricitinib Diamine Impurity be shipped internationally?

Yes. Baricitinib Diamine Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.