6-alpha-Hydroxy MedroxyProgesterone 17-Acetate 984-46-3

About 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate

6-alpha-Hydroxy MedroxyProgesterone 17-Acetate is a metabolite or degradation product of Medroxyprogesterone carrying the CAS registry number 984-46-3. Its molecular formula is C24H34O5 and its molecular weight is 402.5 g/mol. Common synonyms include 6α-Hydroxy Medroxy Progesterone 17-Acetate and 6-Hmap.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Medroxyprogesterone, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Medroxyprogesterone

View every impurity, metabolite and intermediate we list for Medroxyprogesterone.

Medroxyprogesterone impurities

Specifications & identifiers

Chemical identifiers
Product name	6-alpha-Hydroxy MedroxyProgesterone 17-Acetate
Catalogue No.	VQ-026587
CAS Number	984-46-3
IUPAC name	[(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6-hydroxy-6,10,13-trimethyl-3-oxo-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate
Molecular formula	C₂₄H₃₄O₅
Molecular weight	402.5 g/mol
Exact mass	402.2406
Grade	Reference Standard
HSN code	38229090
InChIKey	BIIFPBLHBAQCTJ-NHYVCAMTSA-N
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C[C@](C4=CC(=O)CC[C@]34C)(C)O)C)OC(=O)C
PubChem CID	21122966

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 5
TPSA	80.7 Å²
Synonyms	6α-Hydroxy Medroxy Progesterone 17-Acetate, 6-Hmap, 6-Hydroxy-6-methyl-17-acetoxyprogesterone, Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-hydroxy-6-methyl-, (6alpha)-, 6-hydroxy-6-methyl-3,20-dioxopregn-4-en-17-yl acetate, 6a-Hydroxy Medroxy Progesterone 17-Acetate, 6alpha-Hydroxymedroxyprogesterone Acetate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate?

The CAS Registry Number of 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate is 984-46-3. It is also known as 6α-Hydroxy Medroxy Progesterone 17-Acetate, 6-Hmap, 6-Hydroxy-6-methyl-17-acetoxyprogesterone.

What is the molecular formula and molecular weight of 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate?

6-alpha-Hydroxy MedroxyProgesterone 17-Acetate has the molecular formula C24H34O5 and a molecular weight of 402.5 g/mol. Its IUPAC name is [(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6-hydroxy-6,10,13-trimethyl-3-oxo-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate.

What is 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate used for?

6-alpha-Hydroxy MedroxyProgesterone 17-Acetate is supplied as a characterised reference material related to Medroxyprogesterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate can I order?

We supply 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate?

Yes. Every lot of 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate be shipped internationally?

Yes. 6-alpha-Hydroxy MedroxyProgesterone 17-Acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.