6-Fluoro-2-(oxiran-2-yl)chroman

Name: 6-Fluoro-2-(oxiran-2-yl)chroman
Brand: Vaqora Chemicals
SKU: VQ-032074

About 6-Fluoro-2-(oxiran-2-yl)chroman

6-Fluoro-2-(oxiran-2-yl)chroman (CAS 99199-90-3) is an impurity of Nebivolol offered by Vaqora Chemicals. Its molecular formula is C11H11FO2 and its molecular weight is 194.2 g/mol. The IUPAC name is 6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene. Alternative names: 6-fluoro-2-(oxiran-2-yl)chromane and (S)-6-fluoro-2-((R)-oxiran-2-yl)chroman.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Nebivolol to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 6-Fluoro-2-(oxiran-2-yl)chroman in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nebivolol

View every impurity, metabolite and intermediate we list for Nebivolol.

Nebivolol impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Fluoro-2-(oxiran-2-yl)chroman
Catalogue No.	VQ-032074
CAS Number	99199-90-3
IUPAC name	6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene
Molecular formula	C₁₁H₁₁FO₂
Molecular weight	194.2 g/mol
Exact mass	194.0743
Grade	Reference Standard
HSN code	38229090
InChIKey	GVZDIJGBXSDSEP-UHFFFAOYSA-N
SMILES	C1CC2=C(C=CC(=C2)F)OC1C3CO3
PubChem CID	11658439

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 3
TPSA	21.8 Å²
Synonyms	6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran, 6-fluoro-2-(oxiran-2-yl)chromane, (2R)-rel-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran, (S)-6-fluoro-2-((R)-oxiran-2-yl)chroman, (2R,2'R)-6-Fluoro-2-(2'-oxiranyl)chromane, (2S, 2'S)-6-Fluoro-2-(2'-oxiranyl)chromane, (2S)-6-fluoro-2-[(2S)-oxiran-2-yl]-3,4-dihydro-2H-chromene, 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-(2R)-2-oxiranyl-, (2R)-rel-, Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran, 6-Fluoro-2-oxiranyl-3,4-Dihydro-2H-1-Benzopyran, 6-fluoro-3, 4-dihydro-2-oxiranyl-2h-1-benzopyran, (-)-(R,R)-6-Fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P272, P273, P280, P302 + P352, P321, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Fluoro-2-(oxiran-2-yl)chroman?

The CAS Registry Number of 6-Fluoro-2-(oxiran-2-yl)chroman is 99199-90-3. It is also known as 6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran, 6-fluoro-2-(oxiran-2-yl)chromane, (2R)-rel-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran.

What is the molecular formula and molecular weight of 6-Fluoro-2-(oxiran-2-yl)chroman?

6-Fluoro-2-(oxiran-2-yl)chroman has the molecular formula C11H11FO2 and a molecular weight of 194.2 g/mol. Its IUPAC name is 6-fluoro-2-(oxiran-2-yl)-3,4-dihydro-2H-chromene.

What is 6-Fluoro-2-(oxiran-2-yl)chroman used for?

6-Fluoro-2-(oxiran-2-yl)chroman is supplied as a characterised reference material related to Nebivolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Fluoro-2-(oxiran-2-yl)chroman can I order?

We supply 6-Fluoro-2-(oxiran-2-yl)chroman in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Fluoro-2-(oxiran-2-yl)chroman?

Yes. Every lot of 6-Fluoro-2-(oxiran-2-yl)chroman is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Fluoro-2-(oxiran-2-yl)chroman be shipped internationally?

Yes. 6-Fluoro-2-(oxiran-2-yl)chroman is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.