2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine
Synonyms: 5-Nitro-3-(trifluoromethyl)-2(1h)-pyridinone · 5-nitro-3-(trifluoromethyl)pyridin-2-ol · 5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one · 2(1H)-Pyridinone, 5-nitro-3-(trifluoromethyl)-
2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine (CAS 99368-66-8) – Apalutamide impurity standard. C6H3F3N2O3, MW 208.09. Vaqora Chemicals: COA, global shipping.
About 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine
Listed under CAS 99368-66-8, 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine is a metabolite or degradation product of Apalutamide available from Vaqora Chemicals. Its molecular formula is C6H3F3N2O3 and its molecular weight is 208.09 g/mol. The IUPAC name is 5-nitro-3-(trifluoromethyl)-1H-pyridin-2-one. It is also known as 5-Nitro-3-(trifluoromethyl)-2(1h)-pyridinone or 5-nitro-3-(trifluoromethyl)pyridin-2-ol.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.
It is used in metabolite identification, stability-indicating method development and impurity profiling of Apalutamide, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
- Fine chemical synthesis
Industries
View every impurity, metabolite and intermediate we list for Apalutamide.
Apalutamide impuritiesSpecifications & identifiers
| Product name | 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine |
|---|---|
| Catalogue No. | VQ-032552 |
| CAS Number | 99368-66-8 |
| IUPAC name | 5-nitro-3-(trifluoromethyl)-1H-pyridin-2-one |
| Molecular formula | C6H3F3N2O3 |
| Molecular weight | 208.09 g/mol |
| Exact mass | 208.0096 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | BHUILUYFGJBXHQ-UHFFFAOYSA-N |
| SMILES | C1=C(C(=O)NC=C1[N+](=O)[O-])C(F)(F)F |
| PubChem CID | 2775095 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 0.6 |
| H-bond donors / acceptors | 1 / 6 |
| TPSA | 74.9 Ų |
| Synonyms | 5-Nitro-3-(trifluoromethyl)-2(1h)-pyridinone, 5-nitro-3-(trifluoromethyl)pyridin-2-ol, 5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one, 2(1H)-Pyridinone, 5-nitro-3-(trifluoromethyl)-, CS-M3575, 5-Nitro-3-trifluoromethyl-pyridin-2-ol, 5-nitro-3-(trifluoromethyl)hydropyridin-2-one |
Documents
Frequently asked questions
What is the CAS number of 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine?
The CAS Registry Number of 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine is 99368-66-8. It is also known as 5-Nitro-3-(trifluoromethyl)-2(1h)-pyridinone, 5-nitro-3-(trifluoromethyl)pyridin-2-ol, 5-Nitro-3-(trifluoromethyl)pyridin-2(1H)-one.
What is the molecular formula and molecular weight of 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine?
2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine has the molecular formula C6H3F3N2O3 and a molecular weight of 208.09 g/mol. Its IUPAC name is 5-nitro-3-(trifluoromethyl)-1H-pyridin-2-one.
What is 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine used for?
2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine is supplied as a characterised reference material related to Apalutamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine can I order?
We supply 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine?
Yes. Every lot of 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine be shipped internationally?
Yes. We export 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine
We reply within one business day with price, pack options, lead time and documentation.
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