4-Chloropyridine-2-carboxamide

Name: 4-Chloropyridine-2-carboxamide
Brand: Vaqora Chemicals
SKU: VQ-039264

About 4-Chloropyridine-2-carboxamide

4-Chloropyridine-2-carboxamide (CAS 99586-65-9) is a process intermediate or related compound of Sorafenib offered by Vaqora Chemicals. Formula C6H5ClN2O, molecular weight 156.57 g/mol. Alternative names: 4-Chloropicolinamide and 4-Chloro-pyridine-2-carboxylic acid amide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Sorafenib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 4-Chloropyridine-2-carboxamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloropyridine-2-carboxamide
Catalogue No.	VQ-039264
CAS Number	99586-65-9
IUPAC name	4-chloropyridine-2-carboxamide
Molecular formula	C₆H₅ClN₂O
Molecular weight	156.57 g/mol
Exact mass	156.009
HSN code	2933
InChIKey	XIHHOUUTBZSYJH-UHFFFAOYSA-N
SMILES	C1=CN=C(C=C1Cl)C(=O)N
PubChem CID	303543

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 2
TPSA	56 Å²
Synonyms	4-Chloropicolinamide, 4-Chloro-pyridine-2-carboxylic acid amide, 2-Pyridinecarboxamide, 4-chloro-, 4-Chloropyridine-2-carboxylic acid amide, 4-Chloro-2-picolinic acid amide, 4-Chloro-pyridine-2-carboxylic acid amide, AldrichCPR, 4-chloro-2-p, 4-chloro-2-pyridine-carboxamide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264, P264 + P265, P270, P272, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloropyridine-2-carboxamide?

The CAS Registry Number of 4-Chloropyridine-2-carboxamide is 99586-65-9. It is also known as 4-Chloropicolinamide, 4-Chloro-pyridine-2-carboxylic acid amide, 2-Pyridinecarboxamide, 4-chloro-.

What is the molecular formula and molecular weight of 4-Chloropyridine-2-carboxamide?

4-Chloropyridine-2-carboxamide has the molecular formula C6H5ClN2O and a molecular weight of 156.57 g/mol. Its IUPAC name is 4-chloropyridine-2-carboxamide.

What is 4-Chloropyridine-2-carboxamide used for?

4-Chloropyridine-2-carboxamide is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloropyridine-2-carboxamide can I order?

We supply 4-Chloropyridine-2-carboxamide, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloropyridine-2-carboxamide?

Yes. Every lot of 4-Chloropyridine-2-carboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloropyridine-2-carboxamide be shipped internationally?

Yes. 4-Chloropyridine-2-carboxamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.