Hydrochlorothiazide

Name: Hydrochlorothiazide
Brand: Vaqora Chemicals
SKU: VQ-004093

About Hydrochlorothiazide

Hydrochlorothiazide (CAS 58-93-5) is a cardiovascular API offered by Vaqora Chemicals (IP/BP/USP grade). The compound has the formula C7H8ClN3O4S2, corresponding to a molecular weight of 297.7 g/mol. Systematically, it is named 6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide. Alternative names: Hypothiazide and Idrotiazide.

The product is provided as a powder. Store in a tightly closed container in a cool, dry and well-ventilated place. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

This API belongs to our cardiovascular and antihypertensive APIs portfolio and is supplied to IP/BP/USP specifications for formulators, contract manufacturers and generic drug developers. It is used across pharmaceutical manufacturing.

We offer Hydrochlorothiazide in 1 kg, 5 kg and 25 kg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Pharmaceutical formulation
Generic drug development

Industries

Related to Hydrochlorothiazide

View every impurity, metabolite and intermediate we list for Hydrochlorothiazide.

Hydrochlorothiazide impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Hydrochlorothiazide
Catalogue No.	VQ-004093
CAS Number	58-93-5
IUPAC name	6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
Molecular formula	C₇H₈ClN₃O₄S₂
Molecular weight	297.7 g/mol
Exact mass	296.9645
Grade	IP/BP/USP
HSN code	2933
InChIKey	JZUFKLXOESDKRF-UHFFFAOYSA-N
SMILES	C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
PubChem CID	3639

Physical properties
Physical form	Powder
LogP (XLogP3)	-0.1
H-bond donors / acceptors	3 / 7
TPSA	135 Å²
Synonyms	Hypothiazide, Idrotiazide, Newtolide, Oretic, Dichlotride, Hydrodiuretic, Hydrosaluric, Apresazide, Diclotride, Thiuretic, Drenol, Hydro-Diuril

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P319, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 58-93-5

Reference Standard

Hydrochlorothiazide

CAS: 58-93-5
Formula: C₇H₈ClN₃O₄S₂
MW: 297.7 g/mol

In stock

Frequently asked questions

What is the CAS number of Hydrochlorothiazide?

The CAS Registry Number of Hydrochlorothiazide is 58-93-5. It is also known as Hypothiazide, Idrotiazide, Newtolide.

What is the molecular formula and molecular weight of Hydrochlorothiazide?

Hydrochlorothiazide has the molecular formula C7H8ClN3O4S2 and a molecular weight of 297.7 g/mol. Its IUPAC name is 6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide.

What is Hydrochlorothiazide used for?

Hydrochlorothiazide is supplied as a characterised reference material related to Hydrochlorothiazide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrochlorothiazide can I order?

We supply Hydrochlorothiazide in IP/BP/USP grade, in 1 kg, 5 kg, 25 kg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrochlorothiazide?

Yes. Every lot of Hydrochlorothiazide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrochlorothiazide be shipped internationally?

Yes. Hydrochlorothiazide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.