(S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol 1006376-60-8

Name: (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol
Brand: Vaqora Chemicals
SKU: VQ-042522

About (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol

(S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol (CAS 1006376-60-8) is an impurity of Ticagrelor offered by Vaqora Chemicals. The compound has the formula C8H7ClF2O, corresponding to a molecular weight of 192.59 g/mol. Its systematic (IUPAC) name is (1S)-2-chloro-1-(3,4-difluorophenyl)ethanol. Alternative names: (S)-2-Chloro-1-(3,4-difluorophenyl)ethanol and (S)-2-Chloro-1-(3,4-difluoro-phenyl)-ethanol.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

This Ticagrelor impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ticagrelor

View every impurity, metabolite and intermediate we list for Ticagrelor.

Ticagrelor impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol
Catalogue No.	VQ-042522
CAS Number	1006376-60-8
IUPAC name	(1S)-2-chloro-1-(3,4-difluorophenyl)ethanol
Molecular formula	C₈H₇ClF₂O
Molecular weight	192.59 g/mol
Exact mass	192.0153
Grade	Reference Standard
HSN code	38229090
InChIKey	RYOLLNVCYSUXCP-MRVPVSSYSA-N
SMILES	C1=CC(=C(C=C1[C@@H](CCl)O)F)F
PubChem CID	25324204

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	1 / 3
TPSA	20.2 Å²
Synonyms	(alphaS)-alpha-(Chloromethyl)-3,4-difluorobenzenemethanol, (S)-2-Chloro-1-(3,4-difluorophenyl)ethanol, (1S)-2-Chloro-1-(3,4-difluorophenyl)ethan-1-ol, (1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol, Benzenemethanol, alpha-(chloromethyl)-3,4-difluoro-, (alphaS)-, (S)-2-Chloro-1-(3,4-difluoro-phenyl)-ethanol, (S)-2-Chloro-1-(3,4-Difluorophenyl) Ethanol, Benzenemethanol, alpha-(chloromethyl)-3,4-difluoro-, Benzenemethanol,, A-(chloromethyl)-3,4-difluoro-, (, AS)-

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements: P233, P260, P261, P264, P264 + P265, P270, P271, P272, P280, P284, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol?

The CAS Registry Number of (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol is 1006376-60-8. It is also known as (alphaS)-alpha-(Chloromethyl)-3,4-difluorobenzenemethanol, (S)-2-Chloro-1-(3,4-difluorophenyl)ethanol, (1S)-2-Chloro-1-(3,4-difluorophenyl)ethan-1-ol.

What is the molecular formula and molecular weight of (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol?

(S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol has the molecular formula C8H7ClF2O and a molecular weight of 192.59 g/mol. Its IUPAC name is (1S)-2-chloro-1-(3,4-difluorophenyl)ethanol.

What is (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol used for?

(S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol is supplied as a characterised reference material related to Ticagrelor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol can I order?

We supply (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol?

Yes. Every lot of (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol be shipped internationally?

Yes. (S)-2-Chloro-1-(3,4difluorophenyl)ethan-1-ol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.