1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine 762240-99-3

Name: 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine
Brand: Vaqora Chemicals
SKU: VQ-033873

About 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine

Vaqora Chemicals supplies 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine, an impurity of Sitagliptin registered under CAS number 762240-99-3. Formula C4H4ClF3N2O2, molecular weight 204.53 g/mol. Its systematic (IUPAC) name is N'-(2-chloroacetyl)-2,2,2-trifluoroacetohydrazide. Common synonyms include CS-M0689 and N'-(2-chloroacetyl)-trifluoroacetohydrazide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Sitagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine
Catalogue No.	VQ-033873
CAS Number	762240-99-3
IUPAC name	N'-(2-chloroacetyl)-2,2,2-trifluoroacetohydrazide
Molecular formula	C₄H₄ClF₃N₂O₂
Molecular weight	204.53 g/mol
Exact mass	203.9913
Grade	Reference Standard
HSN code	38229090
InChIKey	DYKIVKLXFDNBMY-UHFFFAOYSA-N
SMILES	C(C(=O)NNC(=O)C(F)(F)F)Cl
PubChem CID	11961370

Physical properties
Physical form	Solid
LogP (XLogP3)	0.8
H-bond donors / acceptors	2 / 5
TPSA	58.2 Å²
Synonyms	N'-(chloroacetyl)-2,2,2-trifluoroacetohydrazide, Acetic acid, 2,2,2-trifluoro-, 2-(2-chloroacetyl)hydrazide, 2,2,2-Trifluoroacetic Acid 2-(2-Chloroacetyl)hydrazide, 2-chloro-N'-(2,2,2-trifluoroacetyl)acetohydrazide, Acetic acid, trifluoro-, 2-(chloroacetyl)hydrazide, CS-M0689, N'-(2-chloroacetyl)-trifluoroacetohydrazide, N'-(2-chloroacetyl)-2,2,2-trifluoro-acetohydrazide, 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine AldrichCPR, 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine, AldrichCPR

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements: P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine?

The CAS Registry Number of 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine is 762240-99-3. It is also known as N'-(chloroacetyl)-2,2,2-trifluoroacetohydrazide, Acetic acid, 2,2,2-trifluoro-, 2-(2-chloroacetyl)hydrazide, 2,2,2-Trifluoroacetic Acid 2-(2-Chloroacetyl)hydrazide.

What is the molecular formula and molecular weight of 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine?

1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine has the molecular formula C4H4ClF3N2O2 and a molecular weight of 204.53 g/mol. Its IUPAC name is N'-(2-chloroacetyl)-2,2,2-trifluoroacetohydrazide.

What is 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine used for?

1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine can I order?

We supply 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine?

Yes. Every lot of 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine be shipped internationally?

Yes. 1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.