Sitagliptin impurity F

Name: Sitagliptin impurity F
Brand: Vaqora Chemicals
SKU: VQ-033877

About Sitagliptin impurity F

Listed under CAS 1608491-98-0, Sitagliptin impurity F is an impurity of Sitagliptin available from Vaqora Chemicals. Formula C22H24F6N4O2, molecular weight 490.4 g/mol. Common synonyms include Sitagliptin Impurity 63 and Sitagliptin Impurity 161.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Sitagliptin impurity F in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin impurity F
Catalogue No.	VQ-033877
CAS Number	1608491-98-0
IUPAC name	(3R)-3-amino-N-[2-[[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]ethyl]-4-(2,4,5-trifluorophenyl)butanamide
Molecular formula	C₂₂H₂₄F₆N₄O₂
Molecular weight	490.4 g/mol
Exact mass	490.1803
Grade	Reference Standard
HSN code	38229090
InChIKey	KXZDIEYEXQRASS-ZIAGYGMSSA-N
SMILES	C1=C(C(=CC(=C1F)F)F)C[C@H](CC(=O)NCCNC(=O)C[C@@H](CC2=CC(=C(C=C2F)F)F)N)N
PubChem CID	163202909

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	4 / 10
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin impurity F?

The CAS Registry Number of Sitagliptin impurity F is 1608491-98-0. It is also known as (3R,3'R)-N,N'-(Ethane-1,2-diyl)bis(3-amino-4-(2,4,5-trifluorophenyl)butanamide), Sitagliptin Impurity 63, Sitagliptin Impurity 161.

What is the molecular formula and molecular weight of Sitagliptin impurity F?

Sitagliptin impurity F has the molecular formula C22H24F6N4O2 and a molecular weight of 490.4 g/mol. Its IUPAC name is (3R)-3-amino-N-[2-[[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]amino]ethyl]-4-(2,4,5-trifluorophenyl)butanamide.

What is Sitagliptin impurity F used for?

Sitagliptin impurity F is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin impurity F can I order?

We supply Sitagliptin impurity F in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin impurity F?

Yes. Every lot of Sitagliptin impurity F is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin impurity F be shipped internationally?

Yes. We export Sitagliptin impurity F worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.