(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-dif… 486459-98-7

Name: (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid
Brand: Vaqora Chemicals
SKU: VQ-033876

About (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid is an impurity of Sitagliptin carrying the CAS registry number 486459-98-7. With the molecular formula C15H19F2NO4, it has a molar mass of 315.31 g/mol. Systematically, it is named (3R)-4-(2,5-difluorophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Sitagliptin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid
Catalogue No.	VQ-033876
CAS Number	486459-98-7
IUPAC name	(3R)-4-(2,5-difluorophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
Molecular formula	C₁₅H₁₉F₂NO₄
Molecular weight	315.31 g/mol
Exact mass	315.1282
Grade	Reference Standard
HSN code	38229090
InChIKey	DYAISPAQPPRCQC-LLVKDONJSA-N
SMILES	CC(C)(C)OC(=O)N[C@H](CC1=C(C=CC(=C1)F)F)CC(=O)O
PubChem CID	11347588

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 6
TPSA	75.6 Å²
Synonyms	(R)-b-(Boc-amino)-2,5-difluorobenzenebutanoic acid, (3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,5-difluorophenyl)butanoic Acid, (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,5-difluorophenyl)butanoic acid, (R)-b-(Boc-amino)-2,5-difluorobenzenebutanoicacid, (R)-b-(Boc-amino)-25-difluorobenzenebutanoic acid, (R)-beta-(Boc-amino)-2,5-difluorobenzenebutanoic acid, (R)-3-(Boc-amino)-4-(2,5-difluorophenyl)butanoic Acid, (3R)-3-(tert-butoxycarbonylamino)-4-(2,5-difluorophenyl)butanoic acid, 3-[(tert-Butoxycarbonyl)amino]-4-(2,5-difluorophenyl)butanoic acid, (3R)-, (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]4-(2,5-difluorophenyl)butanoic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid?

The CAS Registry Number of (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid is 486459-98-7. It is also known as (R)-b-(Boc-amino)-2,5-difluorobenzenebutanoic acid, (3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,5-difluorophenyl)butanoic Acid, (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,5-difluorophenyl)butanoic acid.

What is the molecular formula and molecular weight of (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid?

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid has the molecular formula C15H19F2NO4 and a molecular weight of 315.31 g/mol. Its IUPAC name is (3R)-4-(2,5-difluorophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid.

What is (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid used for?

(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid can I order?

We supply (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid?

Yes. Every lot of (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid be shipped internationally?

Yes. We export (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,5-difluorophenyl)butanoic Acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.