1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea 871700-18-4

Name: 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea
Brand: Vaqora Chemicals
SKU: VQ-042641

About 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea

1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea (CAS 871700-18-4) is an impurity of Trametinib offered by Vaqora Chemicals. The compound has the formula C10H10FIN2O, corresponding to a molecular weight of 320.1 g/mol. Common synonyms include N-Cyclopropyl-N'-(2-fluoro-4-iodophenyl)urea and Trametinib Intermediate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Trametinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trametinib

View every impurity, metabolite and intermediate we list for Trametinib.

Trametinib impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea
Catalogue No.	VQ-042641
CAS Number	871700-18-4
IUPAC name	1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea
Molecular formula	C₁₀H₁₀FIN₂O
Molecular weight	320.1 g/mol
Exact mass	319.9822
Grade	Reference Standard
HSN code	38229090
InChIKey	GAJDOJAFIZOJMS-UHFFFAOYSA-N
SMILES	C1CC1NC(=O)NC2=C(C=C(C=C2)I)F
PubChem CID	59717054

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	2 / 2
TPSA	41.1 Å²
Synonyms	N-Cyclopropyl-N'-(2-fluoro-4-iodophenyl)urea, Urea, N-cyclopropyl-N'-(2-fluoro-4-iodophenyl)-, Trametinib Intermediate, RMA-838, CS-M0419

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea?

The CAS Registry Number of 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea is 871700-18-4. It is also known as N-Cyclopropyl-N'-(2-fluoro-4-iodophenyl)urea, Urea, N-cyclopropyl-N'-(2-fluoro-4-iodophenyl)-, Trametinib Intermediate.

What is the molecular formula and molecular weight of 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea?

1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea has the molecular formula C10H10FIN2O and a molecular weight of 320.1 g/mol. Its IUPAC name is 1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea.

What is 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea used for?

1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea is supplied as a characterised reference material related to Trametinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea can I order?

We supply 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea?

Yes. Every lot of 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea be shipped internationally?

Yes. We export 1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)urea worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.