(1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropa… 2166301-04-6

Name: (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine
Brand: Vaqora Chemicals
SKU: VQ-042545

About (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine

(1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine (CAS 2166301-04-6) is an impurity of Trametinib offered by Vaqora Chemicals. Its molecular formula is C9H9ClFN and its molecular weight is 185.62 g/mol. Its systematic (IUPAC) name is trans-(1S,2R)-2-(4-chloro-3-fluorophenyl)cyclopropan-1-amine. Alternative names: 2-(4-Chloro-3-fluorophenyl)cyclopropanamine.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Trametinib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trametinib

View every impurity, metabolite and intermediate we list for Trametinib.

Trametinib impurities

Specifications & identifiers

Chemical identifiers
Product name	(1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine
Catalogue No.	VQ-042545
CAS Number	2166301-04-6
IUPAC name	trans-(1S,2R)-2-(4-chloro-3-fluorophenyl)cyclopropan-1-amine
Molecular formula	C₉H₉ClFN
Molecular weight	185.62 g/mol
Exact mass	185.0408
Grade	Reference Standard
HSN code	38229090
InChIKey	LVNZCEIVEMZSLV-MUWHJKNJSA-N
SMILES	C1[C@@H]([C@H]1N)C2=CC(=C(C=C2)Cl)F
PubChem CID	93954688

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 2
TPSA	26 Å²
Synonyms	(1S,2R)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine, (1S,2R)-rel-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine, 2-(4-Chloro-3-fluorophenyl)cyclopropanamine, Cyclopropanamine, 2-(4-chloro-3-fluorophenyl)-, trans-2-(4-Chloro-3-fluorophenyl)cyclopropanamine, rel-(1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropanamine, Cyclopropanamine, 2-(4-chloro-3-fluorophenyl)-, (1R,2S)-rel-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine?

The CAS Registry Number of (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine is 2166301-04-6. It is also known as (1S,2R)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine, (1S,2R)-rel-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine, 2-(4-Chloro-3-fluorophenyl)cyclopropanamine.

What is the molecular formula and molecular weight of (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine?

(1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine has the molecular formula C9H9ClFN and a molecular weight of 185.62 g/mol. Its IUPAC name is trans-(1S,2R)-2-(4-chloro-3-fluorophenyl)cyclopropan-1-amine.

What is (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine used for?

(1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine is supplied as a characterised reference material related to Trametinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine can I order?

We supply (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine?

Yes. Every lot of (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine be shipped internationally?

Yes. We export (1R,2S)-2-(4-Chloro-3-fluorophenyl)cyclopropan-1-amine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.