1-Fluoro-5-methoxy-2,4-dinitrobenzene

Name: 1-Fluoro-5-methoxy-2,4-dinitrobenzene
Brand: Vaqora Chemicals
SKU: VQ-012859

About 1-Fluoro-5-methoxy-2,4-dinitrobenzene

1-Fluoro-5-methoxy-2,4-dinitrobenzene is a process intermediate or related compound of Osimertinib carrying the CAS registry number 394-18-3, specified at 99% purity. The compound has the formula C7H5FN2O5, corresponding to a molecular weight of 216.12 g/mol. Alternative names: 2,4-Dinitro-5-fluoroanisole and 1-Fluoro-5-methoxy-2,4-dinitro-benzene.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Osimertinib, useful for route development, impurity fate-and-purge studies and analytical method development. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 1-Fluoro-5-methoxy-2,4-dinitrobenzene in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	1-Fluoro-5-methoxy-2,4-dinitrobenzene
Catalogue No.	VQ-012859
CAS Number	394-18-3
IUPAC name	1-fluoro-5-methoxy-2,4-dinitrobenzene
Molecular formula	C₇H₅FN₂O₅
Molecular weight	216.12 g/mol
Exact mass	216.0182
Grade	Reference Standard
Purity / assay	99%
InChIKey	BKYHMDNLFGUECN-UHFFFAOYSA-N
SMILES	COC1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])F
PubChem CID	88917856

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	0 / 6
TPSA	101 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-Fluoro-5-methoxy-2,4-dinitrobenzene?

The CAS Registry Number of 1-Fluoro-5-methoxy-2,4-dinitrobenzene is 394-18-3. It is also known as 2,4-Dinitro-5-fluoroanisole, 1-Fluoro-5-methoxy-2,4-dinitro-benzene, C7H5FN2O5.

What is the molecular formula and molecular weight of 1-Fluoro-5-methoxy-2,4-dinitrobenzene?

1-Fluoro-5-methoxy-2,4-dinitrobenzene has the molecular formula C7H5FN2O5 and a molecular weight of 216.12 g/mol. Its IUPAC name is 1-fluoro-5-methoxy-2,4-dinitrobenzene.

What is 1-Fluoro-5-methoxy-2,4-dinitrobenzene used for?

1-Fluoro-5-methoxy-2,4-dinitrobenzene is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-Fluoro-5-methoxy-2,4-dinitrobenzene can I order?

We supply 1-Fluoro-5-methoxy-2,4-dinitrobenzene in Reference Standard (99%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-Fluoro-5-methoxy-2,4-dinitrobenzene?

Yes. Every lot of 1-Fluoro-5-methoxy-2,4-dinitrobenzene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-Fluoro-5-methoxy-2,4-dinitrobenzene be shipped internationally?

Yes. We export 1-Fluoro-5-methoxy-2,4-dinitrobenzene worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.