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VAQORACHEMICALS
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Osimertinib

Synonyms: AZD 9291 · Tagrisso · AZD-9291 · Osimertinib (AZD9291)

CAS No.1421373-65-0
FormulaC28H33N7O2
Mol. weight499.60
Catalogue No.VQ-007637
PurityReference Standard
HSN38229090

Osimertinib (CAS 1421373-65-0) – Osimertinib reference standard. C28H33N7O2, MW 499.6. Request a quote: COA, bulk packs and worldwide export.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
250 mg
500 mg
1 g
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About Osimertinib

Vaqora Chemicals supplies Osimertinib, a high-purity reference standard of Osimertinib registered under CAS number 1421373-65-0. Formula C28H33N7O2, molecular weight 499.6 g/mol. Alternative names: AZD 9291 and Tagrisso.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Osimertinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

  • Identification & assay
  • Method development & validation
  • QC reference material

Industries

Related to Osimertinib

View every impurity, metabolite and intermediate we list for Osimertinib.

Osimertinib impurities

Specifications & identifiers

Chemical identifiers
Product nameOsimertinib
Catalogue No.VQ-007637
CAS Number1421373-65-0
Other CAS1421373-66-1
IUPAC nameN-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
Molecular formulaC28H33N7O2
Molecular weight499.6 g/mol
Exact mass499.2696
GradeReference Standard
HSN code38229090
InChIKeyDUYJMQONPNNFPI-UHFFFAOYSA-N
SMILESCN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC
PubChem CID71496458
Physical properties
Physical formSolid
LogP (XLogP3)3.7
H-bond donors / acceptors2 / 7
TPSA87.6 Ų
SynonymsAZD 9291, Tagrisso, AZD-9291, Osimertinib (AZD9291), AZD 9291(Osimertinib), Osimertinib (Standard), AZD9291 (Osimertinib), Osimertinib, mereletinib (obsolete INN), AZD-9291(Osimertinib)?, EX-A314

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant
GHS08 Health hazard
Health hazard
GHS09 Environmental hazard
Environmental hazard

Signal word: Danger

Hazard statements

  • H302Harmful if swallowed
  • H317May cause an allergic skin reaction
  • H360May damage fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure
  • H373May causes damage to organs through prolonged or repeated exposure
  • H400Very toxic to aquatic life
  • H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Osimertinib?

The CAS Registry Number of Osimertinib is 1421373-65-0. It is also known as AZD 9291, Tagrisso, AZD-9291.

What is the molecular formula and molecular weight of Osimertinib?

Osimertinib has the molecular formula C28H33N7O2 and a molecular weight of 499.6 g/mol. Its IUPAC name is N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide.

What is Osimertinib used for?

Osimertinib is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Osimertinib can I order?

We supply Osimertinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Osimertinib?

Yes. Every lot of Osimertinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Osimertinib be shipped internationally?

Yes. Osimertinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about Osimertinib

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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