Osimertinib
Synonyms: AZD 9291 · Tagrisso · AZD-9291 · Osimertinib (AZD9291)
Osimertinib (CAS 1421373-65-0) – Osimertinib reference standard. C28H33N7O2, MW 499.6. Request a quote: COA, bulk packs and worldwide export.
About Osimertinib
Vaqora Chemicals supplies Osimertinib, a high-purity reference standard of Osimertinib registered under CAS number 1421373-65-0. Formula C28H33N7O2, molecular weight 499.6 g/mol. Alternative names: AZD 9291 and Tagrisso.
The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.
As a reference sample of Osimertinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.
Typical applications
- Identification & assay
- Method development & validation
- QC reference material
Industries
View every impurity, metabolite and intermediate we list for Osimertinib.
Osimertinib impuritiesSpecifications & identifiers
| Product name | Osimertinib |
|---|---|
| Catalogue No. | VQ-007637 |
| CAS Number | 1421373-65-0 |
| Other CAS | 1421373-66-1 |
| IUPAC name | N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide |
| Molecular formula | C28H33N7O2 |
| Molecular weight | 499.6 g/mol |
| Exact mass | 499.2696 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | DUYJMQONPNNFPI-UHFFFAOYSA-N |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC |
| PubChem CID | 71496458 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 3.7 |
| H-bond donors / acceptors | 2 / 7 |
| TPSA | 87.6 Ų |
| Synonyms | AZD 9291, Tagrisso, AZD-9291, Osimertinib (AZD9291), AZD 9291(Osimertinib), Osimertinib (Standard), AZD9291 (Osimertinib), Osimertinib, mereletinib (obsolete INN), AZD-9291(Osimertinib)?, EX-A314 |
Safety & hazard information (GHS)
Signal word: Danger
Hazard statements
H302Harmful if swallowedH317May cause an allergic skin reactionH360May damage fertility or the unborn childH372Causes damage to organs through prolonged or repeated exposureH373May causes damage to organs through prolonged or repeated exposureH400Very toxic to aquatic lifeH410Very toxic to aquatic life with long lasting effects
Precautionary statements: P203, P260, P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P391, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Osimertinib?
The CAS Registry Number of Osimertinib is 1421373-65-0. It is also known as AZD 9291, Tagrisso, AZD-9291.
What is the molecular formula and molecular weight of Osimertinib?
Osimertinib has the molecular formula C28H33N7O2 and a molecular weight of 499.6 g/mol. Its IUPAC name is N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide.
What is Osimertinib used for?
Osimertinib is supplied as a characterised reference material related to Osimertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Osimertinib can I order?
We supply Osimertinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Osimertinib?
Yes. Every lot of Osimertinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Osimertinib be shipped internationally?
Yes. Osimertinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Osimertinib
We reply within one business day with price, pack options, lead time and documentation.