10-Oxo Naloxone

Name: 10-Oxo Naloxone
Brand: Vaqora Chemicals
SKU: VQ-044552

About 10-Oxo Naloxone

10-Oxo Naloxone is an impurity of Naloxone carrying the CAS registry number 294175-43-2. Its molecular formula is C19H19NO5 and its molecular weight is 341.4 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Naloxone impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 10-Oxo Naloxone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Naloxone

View every impurity, metabolite and intermediate we list for Naloxone.

Naloxone impurities

Specifications & identifiers

Chemical identifiers
Product name	10-Oxo Naloxone
Catalogue No.	VQ-044552
CAS Number	294175-43-2
IUPAC name	(4S,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7a-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,13-dione
Molecular formula	C₁₉H₁₉NO₅
Molecular weight	341.4 g/mol
Exact mass	341.1263
Grade	Reference Standard
HSN code	38229090
InChIKey	IKMNPTIPIBFNPV-YDZRNGNQSA-N
SMILES	C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1C(=O)C5=C3C(=C(C=C5)O)O4)O
PubChem CID	9905989

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 6
TPSA	87.1 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 10-Oxo Naloxone?

The CAS Registry Number of 10-Oxo Naloxone is 294175-43-2.

What is the molecular formula and molecular weight of 10-Oxo Naloxone?

10-Oxo Naloxone has the molecular formula C19H19NO5 and a molecular weight of 341.4 g/mol. Its IUPAC name is (4S,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-1,2,4,5,6,7a-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7,13-dione.

What is 10-Oxo Naloxone used for?

10-Oxo Naloxone is supplied as a characterised reference material related to Naloxone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 10-Oxo Naloxone can I order?

We supply 10-Oxo Naloxone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 10-Oxo Naloxone?

Yes. Every lot of 10-Oxo Naloxone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 10-Oxo Naloxone be shipped internationally?

Yes. 10-Oxo Naloxone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.