Naloxone

Name: Naloxone
Brand: Vaqora Chemicals
SKU: VQ-007597

About Naloxone

Naloxone (CAS 465-65-6) is a high-purity reference standard of Naloxone offered by Vaqora Chemicals. With the molecular formula C19H21NO4, it has a molar mass of 327.4 g/mol. Alternative names: l-Naloxone and (-)-Naloxone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Naloxone standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Naloxone in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Naloxone

View every impurity, metabolite and intermediate we list for Naloxone.

Naloxone impurities

Specifications & identifiers

Chemical identifiers
Product name	Naloxone
Catalogue No.	VQ-007597
CAS Number	465-65-6
Other CAS	357-08-4, 51481-60-8
IUPAC name	(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular formula	C₁₉H₂₁NO₄
Molecular weight	327.4 g/mol
Exact mass	327.1471
Grade	Reference Standard
HSN code	38229090
InChIKey	UZHSEJADLWPNLE-GRGSLBFTSA-N
SMILES	C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O
PubChem CID	5284596

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 5
TPSA	70 Å²
Synonyms	(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one, l-Naloxone, (-)-Naloxone, n-Allylnoroxymorphone, EN 1530 base, Nalossone, N-Allyl-noroxymorphone, DBL Naloxone, 1-N-Allyl-14-hydroxynordihydromorphinone, Naloxone Nasal Spray, 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one, 1-N-Allyl-7,8-dihydro-14-hydroxynormorphinone

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Naloxone?

The CAS Registry Number of Naloxone is 465-65-6. It is also known as (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propen-1-yl)morphinan-6-one, l-Naloxone, (-)-Naloxone.

What is the molecular formula and molecular weight of Naloxone?

Naloxone has the molecular formula C19H21NO4 and a molecular weight of 327.4 g/mol. Its IUPAC name is (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

What is Naloxone used for?

Naloxone is supplied as a characterised reference material related to Naloxone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Naloxone can I order?

We supply Naloxone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Naloxone?

Yes. Every lot of Naloxone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Naloxone be shipped internationally?

Yes. Naloxone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.