15-O-Desmethyl tacrolimus

Name: 15-O-Desmethyl tacrolimus
Brand: Vaqora Chemicals
SKU: VQ-042332

About 15-O-Desmethyl tacrolimus

15-O-Desmethyl tacrolimus (CAS 151039-41-7) is a metabolite or degradation product of Tacrolimus offered by Vaqora Chemicals. With the molecular formula C43H67NO12, it has a molar mass of 790.0 g/mol. Common synonyms include Tacrolimus 15-DMT.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tacrolimus, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 15-O-Desmethyl tacrolimus in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	15-O-Desmethyl tacrolimus
Catalogue No.	VQ-042332
CAS Number	151039-41-7
IUPAC name	(1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-1,14,23-trihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-25-methoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Molecular formula	C₄₃H₆₇NO₁₂
Molecular weight	790 g/mol
Exact mass	789.4663
Grade	Reference Standard
HSN code	38229090
InChIKey	ZQRSWRVAAABQEF-DUGRZSFISA-N
SMILES	C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](C=C(C1)C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)O
PubChem CID	176478114

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	4 / 12
TPSA	189 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 15-O-Desmethyl tacrolimus?

The CAS Registry Number of 15-O-Desmethyl tacrolimus is 151039-41-7. It is also known as Tacrolimus 15-DMT.

What is the molecular formula and molecular weight of 15-O-Desmethyl tacrolimus?

15-O-Desmethyl tacrolimus has the molecular formula C43H67NO12 and a molecular weight of 790 g/mol.

What is 15-O-Desmethyl tacrolimus used for?

15-O-Desmethyl tacrolimus is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 15-O-Desmethyl tacrolimus can I order?

We supply 15-O-Desmethyl tacrolimus in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 15-O-Desmethyl tacrolimus?

Yes. Every lot of 15-O-Desmethyl tacrolimus is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 15-O-Desmethyl tacrolimus be shipped internationally?

Yes. We export 15-O-Desmethyl tacrolimus worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.