31-O-Desmethyl tacrolimus

Name: 31-O-Desmethyl tacrolimus
Brand: Vaqora Chemicals
SKU: VQ-042333

About 31-O-Desmethyl tacrolimus

31-O-Desmethyl tacrolimus is a metabolite or degradation product of Tacrolimus carrying the CAS registry number 135635-47-1. Its molecular formula is C43H67NO12 and its molecular weight is 790.0 g/mol. Common synonyms include 31-O-Demethyl-FK506 and 31-O-Demethyl-FK-506.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Tacrolimus, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer 31-O-Desmethyl tacrolimus in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Specifications & identifiers

Chemical identifiers
Product name	31-O-Desmethyl tacrolimus
Catalogue No.	VQ-042333
CAS Number	135635-47-1
IUPAC name	(18E)-12-[(E)-1-(3,4-dihydroxycyclohexyl)prop-1-en-2-yl]-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Molecular formula	C₄₃H₆₇NO₁₂
Molecular weight	790 g/mol
Exact mass	789.4663
Grade	Reference Standard
HSN code	38229090
InChIKey	VHOPGJHKSPGXIZ-AMASXYNMSA-N
SMILES	CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(/C=C(/C1)\C)CC=C)O)C)/C(=C/C4CCC(C(C4)O)O)/C)O)C)OC)OC
PubChem CID	6444024

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	4 / 12
TPSA	189 Å²
Synonyms	31-O-Demethyl-FK506, 31-O-Demethyl-FK-506, 31-O-demethylFK506, 31-O-desmethylFK-506, 31-O-demethylFK-506

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 31-O-Desmethyl tacrolimus?

The CAS Registry Number of 31-O-Desmethyl tacrolimus is 135635-47-1. It is also known as 31-O-Demethyl-FK506, 31-O-Demethyl-FK-506, 31-O-demethylFK506.

What is the molecular formula and molecular weight of 31-O-Desmethyl tacrolimus?

31-O-Desmethyl tacrolimus has the molecular formula C43H67NO12 and a molecular weight of 790 g/mol.

What is 31-O-Desmethyl tacrolimus used for?

31-O-Desmethyl tacrolimus is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 31-O-Desmethyl tacrolimus can I order?

We supply 31-O-Desmethyl tacrolimus in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 31-O-Desmethyl tacrolimus?

Yes. Every lot of 31-O-Desmethyl tacrolimus is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 31-O-Desmethyl tacrolimus be shipped internationally?

Yes. We export 31-O-Desmethyl tacrolimus worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.