Tacrolimus-13C,d2

Name: Tacrolimus-13C,d2
Brand: Vaqora Chemicals
SKU: VQ-042336

About Tacrolimus-13C,d2

Listed under CAS 1356841-89-8, Tacrolimus-13C,d2 is a stable isotope labelled analogue related to Tacrolimus available from Vaqora Chemicals. Its molecular formula is C44H69NO12 and its molecular weight is 807.0 g/mol. Common synonyms include FK-506-13C,D2 (Major) (Tacrolimus) and FK-506-13C-d2.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Tacrolimus and related analytes in bioanalytical, pharmacokinetic and impurity studies. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Tacrolimus

View every impurity, metabolite and intermediate we list for Tacrolimus.

Tacrolimus impurities

Grade guides

Specifications & identifiers

Chemical identifiers
Product name	Tacrolimus-13C,d2
Catalogue No.	VQ-042336
CAS Number	1356841-89-8
IUPAC name	(1R,9S,12S,13R,14S,17R,18Z,21S,23S,24R,25S,27R)-17-(3,3-dideuterio(313C)prop-2-enyl)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Molecular formula	C₄₄H₆₉NO₁₂
Molecular weight	807 g/mol
Exact mass	806.4979
Grade	Reference Standard
HSN code	38229090
InChIKey	QJJXYPPXXYFBGM-OTZVSDQDSA-N
SMILES	[2H][13C](=CC[C@@H]1/C=C(\C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)/C)[2H]
PubChem CID	131708886

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	3 / 12
TPSA	178 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tacrolimus-13C,d2?

The CAS Registry Number of Tacrolimus-13C,d2 is 1356841-89-8. It is also known as FK-506-13C,D2 (Major) (Tacrolimus), FK-506-13C,D2 (Major) (Tacrolimus)(>85per cent), FK-506-13C-d2.

What is the molecular formula and molecular weight of Tacrolimus-13C,d2?

Tacrolimus-13C,d2 has the molecular formula C44H69NO12 and a molecular weight of 807 g/mol.

What is Tacrolimus-13C,d2 used for?

Tacrolimus-13C,d2 is supplied as a characterised reference material related to Tacrolimus. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tacrolimus-13C,d2 can I order?

We supply Tacrolimus-13C,d2 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tacrolimus-13C,d2?

Yes. Every lot of Tacrolimus-13C,d2 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tacrolimus-13C,d2 be shipped internationally?

Yes. We export Tacrolimus-13C,d2 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.