2'-Deoxy-2'-methyleneuridine

Name: 2'-Deoxy-2'-methyleneuridine
Brand: Vaqora Chemicals
SKU: VQ-028896

About 2'-Deoxy-2'-methyleneuridine

2'-Deoxy-2'-methyleneuridine (CAS 119410-95-6) is an impurity of Sofosbuvir offered by Vaqora Chemicals. The compound has the formula C10H12N2O5, corresponding to a molecular weight of 240.21 g/mol. Its systematic (IUPAC) name is 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-methylideneoxolan-2-yl]pyrimidine-2,4-dione. Alternative names: Uridine, 2'-deoxy-2'-methylene- and 2'-deoxy-2'-methylideneuridine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Sofosbuvir impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 2'-Deoxy-2'-methyleneuridine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sofosbuvir

View every impurity, metabolite and intermediate we list for Sofosbuvir.

Sofosbuvir impurities

Specifications & identifiers

Chemical identifiers
Product name	2'-Deoxy-2'-methyleneuridine
Catalogue No.	VQ-028896
CAS Number	119410-95-6
IUPAC name	1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-methylideneoxolan-2-yl]pyrimidine-2,4-dione
Molecular formula	C₁₀H₁₂N₂O₅
Molecular weight	240.21 g/mol
Exact mass	240.0746
Grade	Reference Standard
HSN code	38229090
InChIKey	AHOGIDIXKMOVSP-BWVDBABLSA-N
SMILES	C=C1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)CO)O
PubChem CID	11075548

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.7
H-bond donors / acceptors	3 / 5
TPSA	99.1 Å²
Synonyms	Uridine, 2'-deoxy-2'-methylene-, 2'-deoxy-2'-methylideneuridine, 2'-Methylene-2'-deoxyuridine, 2'-Methylidene-2'-deoxyuridine, Uridine, 2'-deoxy-2'-methylene

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2'-Deoxy-2'-methyleneuridine?

The CAS Registry Number of 2'-Deoxy-2'-methyleneuridine is 119410-95-6. It is also known as Uridine, 2'-deoxy-2'-methylene-, 2'-deoxy-2'-methylideneuridine, 2'-Methylene-2'-deoxyuridine.

What is the molecular formula and molecular weight of 2'-Deoxy-2'-methyleneuridine?

2'-Deoxy-2'-methyleneuridine has the molecular formula C10H12N2O5 and a molecular weight of 240.21 g/mol. Its IUPAC name is 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-methylideneoxolan-2-yl]pyrimidine-2,4-dione.

What is 2'-Deoxy-2'-methyleneuridine used for?

2'-Deoxy-2'-methyleneuridine is supplied as a characterised reference material related to Sofosbuvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2'-Deoxy-2'-methyleneuridine can I order?

We supply 2'-Deoxy-2'-methyleneuridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2'-Deoxy-2'-methyleneuridine?

Yes. Every lot of 2'-Deoxy-2'-methyleneuridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2'-Deoxy-2'-methyleneuridine be shipped internationally?

Yes. We export 2'-Deoxy-2'-methyleneuridine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.