(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxal… 15186-48-8

Name: (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
Brand: Vaqora Chemicals
SKU: VQ-030964

About (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is an impurity of Sofosbuvir carrying the CAS registry number 15186-48-8. Formula C6H10O3, molecular weight 130.14 g/mol. Its systematic (IUPAC) name is (4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde. Common synonyms include (R)-Glyceraldehyde Acetonide and (R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Sofosbuvir impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sofosbuvir

View every impurity, metabolite and intermediate we list for Sofosbuvir.

Sofosbuvir impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde
Catalogue No.	VQ-030964
CAS Number	15186-48-8
IUPAC name	(4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde
Molecular formula	C₆H₁₀O₃
Molecular weight	130.14 g/mol
Exact mass	130.063
Grade	Reference Standard
HSN code	38229090
InChIKey	YSGPYVWACGYQDJ-YFKPBYRVSA-N
SMILES	CC1(OC[C@@H](O1)C=O)C
PubChem CID	259712

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²
Synonyms	(R)-Glyceraldehyde Acetonide, (R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde, (R)-(+)-Glyceraldehyde acetonide, 1,3-Dioxolane-4-carboxaldehyde, 2,2-dimethyl-, (R)-, Acetone D-glyceraldehyde, 1,3-Dioxolane-4-carboxaldehyde, 2,2-dimethyl-, (4R)-, 2,3-o-isopropylidene-d-glyceraldehyde, 2,2-(R)-Dimethyl-1,3-dioxolane-4-carboxaldehyde, 2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde, (D)-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P210, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde?

The CAS Registry Number of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is 15186-48-8. It is also known as (R)-Glyceraldehyde Acetonide, (R)-2,2-Dimethyl-1,3-dioxolane-4-carbaldehyde, (R)-(+)-Glyceraldehyde acetonide.

What is the molecular formula and molecular weight of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde?

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde has the molecular formula C6H10O3 and a molecular weight of 130.14 g/mol. Its IUPAC name is (4R)-2,2-dimethyl-1,3-dioxolane-4-carbaldehyde.

What is (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde used for?

(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is supplied as a characterised reference material related to Sofosbuvir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde can I order?

We supply (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde?

Yes. Every lot of (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde be shipped internationally?

Yes. (R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.