2-Fluoro-6-methoxybenzenesulfonyl chloride 1176126-31-0

Name: 2-Fluoro-6-methoxybenzenesulfonyl chloride
Brand: Vaqora Chemicals
SKU: VQ-029991

About 2-Fluoro-6-methoxybenzenesulfonyl chloride

2-Fluoro-6-methoxybenzenesulfonyl chloride is an impurity of Dabrafenib carrying the CAS registry number 1176126-31-0. Formula C7H6ClFO3S, molecular weight 224.64 g/mol. Common synonyms include 2-Fluoro-6-methoxybenzenesulphonyl Chloride and 2-fluoro-6-methoxybenzene-1-sulfonyl chloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

This Dabrafenib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 2-Fluoro-6-methoxybenzenesulfonyl chloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dabrafenib

View every impurity, metabolite and intermediate we list for Dabrafenib.

Dabrafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Fluoro-6-methoxybenzenesulfonyl chloride
Catalogue No.	VQ-029991
CAS Number	1176126-31-0
IUPAC name	2-fluoro-6-methoxybenzenesulfonyl chloride
Molecular formula	C₇H₆ClFO₃S
Molecular weight	224.64 g/mol
Exact mass	223.971
Grade	Reference Standard
HSN code	38229090
InChIKey	XJAVLIIXUXQDBO-UHFFFAOYSA-N
SMILES	COC1=C(C(=CC=C1)F)S(=O)(=O)Cl
PubChem CID	50998413

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	0 / 4
TPSA	51.8 Å²
Synonyms	2-Fluoro-6-methoxybenzenesulphonyl Chloride, 2-fluoro-6-methoxybenzene-1-sulfonyl chloride, 2-(Chlorosulphonyl)-3-fluoroanisole, 2-Fluoro-6-methoxybenzenesulphonylchloride, Benzenesulfonyl chloride, 2-fluoro-6-methoxy-, 2-Fluoro-6-methoxy-1-benzenesulfonyl Chloride

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H335May cause respiratory irritation

Precautionary statements: P260, P261, P264, P270, P271, P280, P301 + P317, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P319, P321, P330, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Fluoro-6-methoxybenzenesulfonyl chloride?

The CAS Registry Number of 2-Fluoro-6-methoxybenzenesulfonyl chloride is 1176126-31-0. It is also known as 2-Fluoro-6-methoxybenzenesulphonyl Chloride, 2-fluoro-6-methoxybenzene-1-sulfonyl chloride, 2-(Chlorosulphonyl)-3-fluoroanisole.

What is the molecular formula and molecular weight of 2-Fluoro-6-methoxybenzenesulfonyl chloride?

2-Fluoro-6-methoxybenzenesulfonyl chloride has the molecular formula C7H6ClFO3S and a molecular weight of 224.64 g/mol. Its IUPAC name is 2-fluoro-6-methoxybenzenesulfonyl chloride.

What is 2-Fluoro-6-methoxybenzenesulfonyl chloride used for?

2-Fluoro-6-methoxybenzenesulfonyl chloride is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Fluoro-6-methoxybenzenesulfonyl chloride can I order?

We supply 2-Fluoro-6-methoxybenzenesulfonyl chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Fluoro-6-methoxybenzenesulfonyl chloride?

Yes. Every lot of 2-Fluoro-6-methoxybenzenesulfonyl chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Fluoro-6-methoxybenzenesulfonyl chloride be shipped internationally?

Yes. 2-Fluoro-6-methoxybenzenesulfonyl chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.