Carboxy Dabrafenib

Name: Carboxy Dabrafenib
Brand: Vaqora Chemicals
SKU: VQ-025149

About Carboxy Dabrafenib

Carboxy Dabrafenib is a metabolite or degradation product of Dabrafenib carrying the CAS registry number 1195873-54-1. The compound has the formula C23H18F3N5O4S2, corresponding to a molecular weight of 549.5 g/mol. Common synonyms include Dabrafenib Carboxylic Acid and Carboxy darafenib.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Dabrafenib, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Carboxy Dabrafenib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Dabrafenib

View every impurity, metabolite and intermediate we list for Dabrafenib.

Dabrafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Carboxy Dabrafenib
Catalogue No.	VQ-025149
CAS Number	1195873-54-1
IUPAC name	2-[5-(2-aminopyrimidin-4-yl)-4-[3-[(2,6-difluorophenyl)sulfonylamino]-2-fluorophenyl]-1,3-thiazol-2-yl]-2-methylpropanoic acid
Molecular formula	C₂₃H₁₈F₃N₅O₄S₂
Molecular weight	549.5 g/mol
Exact mass	549.0752
Grade	Reference Standard
HSN code	38229090
InChIKey	HYPIMGBMLINCMM-UHFFFAOYSA-N
SMILES	CC(C)(C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F)C(=O)O
PubChem CID	57989831

Physical properties
Physical form	Solid
LogP (XLogP3)	3.5
H-bond donors / acceptors	3 / 13
TPSA	185 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Carboxy Dabrafenib?

The CAS Registry Number of Carboxy Dabrafenib is 1195873-54-1. It is also known as Dabrafenib Carboxylic Acid, Carboxy darafenib, 2-(2-bromo-1-(4-(methylsulfonyl)phenyl)ethoxy)-1-(4-(methylsulfonyl)phenyl)ethan-1-one.

What is the molecular formula and molecular weight of Carboxy Dabrafenib?

Carboxy Dabrafenib has the molecular formula C23H18F3N5O4S2 and a molecular weight of 549.5 g/mol. Its IUPAC name is 2-[5-(2-aminopyrimidin-4-yl)-4-[3-[(2,6-difluorophenyl)sulfonylamino]-2-fluorophenyl]-1,3-thiazol-2-yl]-2-methylpropanoic acid.

What is Carboxy Dabrafenib used for?

Carboxy Dabrafenib is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Carboxy Dabrafenib can I order?

We supply Carboxy Dabrafenib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Carboxy Dabrafenib?

Yes. Every lot of Carboxy Dabrafenib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Carboxy Dabrafenib be shipped internationally?

Yes. We export Carboxy Dabrafenib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.