Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate
Synonyms: Benzoic acid, 3-[[(2,6-difluorophenyl)sulfonyl]amino]-2-fluoro-, methyl ester · Benzoic acid, 3-(((2,6-difluorophenyl)sulfonyl)amino)-2-fluoro-, methyl ester · Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate · Methyl 3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorobenzoate
Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate (CAS 1195768-19-4) – Dabrafenib impurity standard. C14H10F3NO4S, MW 345.3. COA included.
About Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate
Listed under CAS 1195768-19-4, Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate is an impurity of Dabrafenib available from Vaqora Chemicals. With the molecular formula C14H10F3NO4S, it has a molar mass of 345.3 g/mol. Systematically, it is named methyl 3-[(2,6-difluorophenyl)sulfonylamino]-2-fluorobenzoate. Common synonyms include Dalafenib intermediate 3.
It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.
As a characterised impurity of Dabrafenib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Dabrafenib.
Dabrafenib impuritiesSpecifications & identifiers
| Product name | Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate |
|---|---|
| Catalogue No. | VQ-025145 |
| CAS Number | 1195768-19-4 |
| IUPAC name | methyl 3-[(2,6-difluorophenyl)sulfonylamino]-2-fluorobenzoate |
| Molecular formula | C14H10F3NO4S |
| Molecular weight | 345.3 g/mol |
| Exact mass | 345.0283 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | COSCWKICERLCEK-UHFFFAOYSA-N |
| SMILES | COC(=O)C1=C(C(=CC=C1)NS(=O)(=O)C2=C(C=CC=C2F)F)F |
| PubChem CID | 57989692 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 2.6 |
| H-bond donors / acceptors | 1 / 8 |
| TPSA | 80.9 Ų |
| Synonyms | Benzoic acid, 3-[[(2,6-difluorophenyl)sulfonyl]amino]-2-fluoro-, methyl ester, Benzoic acid, 3-(((2,6-difluorophenyl)sulfonyl)amino)-2-fluoro-, methyl ester, Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate, Methyl 3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorobenzoate, Methyl 3-[[(2,6-difluorophenyl)sulfonyl]amino]-2-fluorobenzoate, Dalafenib intermediate 3, methyl 3-(2,6-difluorobenzenesulfonamido)-2-fluorobenzoate, 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate, methyl 3-[(2,6-difluorophenyl)sulfonylamino]-2-fluoro-benzoate |
Documents
Frequently asked questions
What is the CAS number of Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate?
The CAS Registry Number of Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate is 1195768-19-4. It is also known as Benzoic acid, 3-[[(2,6-difluorophenyl)sulfonyl]amino]-2-fluoro-, methyl ester, Benzoic acid, 3-(((2,6-difluorophenyl)sulfonyl)amino)-2-fluoro-, methyl ester, Methyl 3-{[(2,6-difluoropheyl)sulfonyl]amino}-2-fluorabenzoate.
What is the molecular formula and molecular weight of Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate?
Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate has the molecular formula C14H10F3NO4S and a molecular weight of 345.3 g/mol. Its IUPAC name is methyl 3-[(2,6-difluorophenyl)sulfonylamino]-2-fluorobenzoate.
What is Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate used for?
Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate is supplied as a characterised reference material related to Dabrafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate can I order?
We supply Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate?
Yes. Every lot of Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate be shipped internationally?
Yes. We export Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate
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