2,4-Dichloro-nicotinic acid

Name: 2,4-Dichloro-nicotinic acid
Brand: Vaqora Chemicals
SKU: VQ-052375

About 2,4-Dichloro-nicotinic acid

Listed under CAS 262423-77-8, 2,4-Dichloro-nicotinic acid is a process intermediate or related compound of Avatrombopag available from Vaqora Chemicals. With the molecular formula C6H3Cl2NO2, it has a molar mass of 192.0 g/mol. Its systematic (IUPAC) name is 2,4-dichloropyridine-3-carboxylic acid. Common synonyms include 2,4-Dichloronicotinc Acid and 2,4-Dichloro-3-pyridinecarboxylic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Avatrombopag, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 2,4-Dichloro-nicotinic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Avatrombopag

View every impurity, metabolite and intermediate we list for Avatrombopag.

Avatrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	2,4-Dichloro-nicotinic acid
Catalogue No.	VQ-052375
CAS Number	262423-77-8
IUPAC name	2,4-dichloropyridine-3-carboxylic acid
Molecular formula	C₆H₃Cl₂NO₂
Molecular weight	192 g/mol
Exact mass	190.9541
HSN code	2933
InChIKey	ZFGZNVSNOJPGDV-UHFFFAOYSA-N
SMILES	C1=CN=C(C(=C1Cl)C(=O)O)Cl
PubChem CID	10583887

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 3
TPSA	50.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,4-Dichloro-nicotinic acid?

The CAS Registry Number of 2,4-Dichloro-nicotinic acid is 262423-77-8. It is also known as 2,4-Dichloronicotinc Acid, 2,4-Dichloro-3-pyridinecarboxylic acid, 3-Pyridinecarboxylic acid, 2,4-dichloro-.

What is the molecular formula and molecular weight of 2,4-Dichloro-nicotinic acid?

2,4-Dichloro-nicotinic acid has the molecular formula C6H3Cl2NO2 and a molecular weight of 192 g/mol. Its IUPAC name is 2,4-dichloropyridine-3-carboxylic acid.

What is 2,4-Dichloro-nicotinic acid used for?

2,4-Dichloro-nicotinic acid is supplied as a characterised reference material related to Avatrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,4-Dichloro-nicotinic acid can I order?

We supply 2,4-Dichloro-nicotinic acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,4-Dichloro-nicotinic acid?

Yes. Every lot of 2,4-Dichloro-nicotinic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,4-Dichloro-nicotinic acid be shipped internationally?

Yes. 2,4-Dichloro-nicotinic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.