2,5,6-Trichloronicotinic acid

Name: 2,5,6-Trichloronicotinic acid
Brand: Vaqora Chemicals
SKU: VQ-052376

About 2,5,6-Trichloronicotinic acid

2,5,6-Trichloronicotinic acid (CAS 54718-39-7) is a process intermediate or related compound of Avatrombopag offered by Vaqora Chemicals. The compound has the formula C6H2Cl3NO2, corresponding to a molecular weight of 226.4 g/mol. The IUPAC name is 2,5,6-trichloropyridine-3-carboxylic acid. It is also known as 3-Pyridinecarboxylic acid, 2,5,6-trichloro- or 2,5,6-Trichloro-3-pyridinecarboxylic acid.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Avatrombopag, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Avatrombopag

View every impurity, metabolite and intermediate we list for Avatrombopag.

Avatrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	2,5,6-Trichloronicotinic acid
Catalogue No.	VQ-052376
CAS Number	54718-39-7
IUPAC name	2,5,6-trichloropyridine-3-carboxylic acid
Molecular formula	C₆H₂Cl₃NO₂
Molecular weight	226.4 g/mol
Exact mass	224.9151
HSN code	2933
InChIKey	XMJRZCYSCMZVJQ-UHFFFAOYSA-N
SMILES	C1=C(C(=NC(=C1Cl)Cl)Cl)C(=O)O
PubChem CID	4190038

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	1 / 3
TPSA	50.2 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2,5,6-Trichloronicotinic acid?

The CAS Registry Number of 2,5,6-Trichloronicotinic acid is 54718-39-7. It is also known as 3-Pyridinecarboxylic acid, 2,5,6-trichloro-, 2,5,6-Trichloro-3-pyridinecarboxylic acid.

What is the molecular formula and molecular weight of 2,5,6-Trichloronicotinic acid?

2,5,6-Trichloronicotinic acid has the molecular formula C6H2Cl3NO2 and a molecular weight of 226.4 g/mol. Its IUPAC name is 2,5,6-trichloropyridine-3-carboxylic acid.

What is 2,5,6-Trichloronicotinic acid used for?

2,5,6-Trichloronicotinic acid is supplied as a characterised reference material related to Avatrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2,5,6-Trichloronicotinic acid can I order?

We supply 2,5,6-Trichloronicotinic acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2,5,6-Trichloronicotinic acid?

Yes. Every lot of 2,5,6-Trichloronicotinic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2,5,6-Trichloronicotinic acid be shipped internationally?

Yes. 2,5,6-Trichloronicotinic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.