(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpen… 752174-62-2

Name: (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester
Brand: Vaqora Chemicals
SKU: VQ-012743

About (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester (CAS 752174-62-2) is a process intermediate or related compound of Sacubitril offered by Vaqora Chemicals. With the molecular formula C20H25NO2, it has a molar mass of 311.4 g/mol. Its systematic (IUPAC) name is ethyl (2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Process chemists and analysts use it when developing synthetic routes to Sacubitril, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Sacubitril

View every impurity, metabolite and intermediate we list for Sacubitril.

Sacubitril impurities

Specifications & identifiers

Chemical identifiers
Product name	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester
Catalogue No.	VQ-012743
CAS Number	752174-62-2
IUPAC name	ethyl (2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoate
Molecular formula	C₂₀H₂₅NO₂
Molecular weight	311.4 g/mol
Exact mass	311.1885
Grade	Reference Standard
HSN code	2933
InChIKey	OKDSPZRSANXDRL-BEFAXECRSA-N
SMILES	CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)N
PubChem CID	25017087

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 3
TPSA	52.3 Å²
Synonyms	Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate, (2R,4S)-Ethyl 5-[(1,1'-biphenyl)-4-yl]-4-amino-2-methylpentanoate, Ethyl (αR,γS)-γ-amino-α-methyl[1,1′-biphenyl]-4-pentanoate, (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester, (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate, (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid ethyl ester, (2R,4S)-ethyl5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate, 4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester, (2R,4S)-, Ethyl (alphaR,gammaS)-gamma-amino-alpha-methyl[1,1'-biphenyl]-4-pentanoate, [1,1'-Biphenyl]-4-pentanoic acid, gamma-amino-alpha-methyl-, ethyl ester, (alphaR,gammaS)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester?

The CAS Registry Number of (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester is 752174-62-2. It is also known as Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate, (2R,4S)-Ethyl 5-[(1,1'-biphenyl)-4-yl]-4-amino-2-methylpentanoate, Ethyl (αR,γS)-γ-amino-α-methyl[1,1′-biphenyl]-4-pentanoate.

What is the molecular formula and molecular weight of (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester?

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester has the molecular formula C20H25NO2 and a molecular weight of 311.4 g/mol. Its IUPAC name is ethyl (2R,4S)-4-amino-2-methyl-5-(4-phenylphenyl)pentanoate.

What is (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester used for?

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester is supplied as a characterised reference material related to Sacubitril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester can I order?

We supply (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester?

Yes. Every lot of (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester be shipped internationally?

Yes. We export (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.